{"id":"W7143507916","doi":"10.71465/ajpp.2268","title":"Impact of Nutraceuticals on Drug Efficacy and Metabolism","year":2022,"lang":"","type":"article","venue":"American Journal Of Pharmacy And Pharmacology","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Nutraceutical; Drug; Pharmacodynamics; Clinical efficacy; Pharmacokinetics; Adverse effect; Efficacy; Drug development","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001022956,0.0003538755,0.0006573992,0.0004368271,0.0001729866,0.0009260358,0.0002158588,0.0004995812,0.003559981],"category_scores_gemma":[0.002465888,0.0001503212,0.0008113605,0.0003630011,0.0003077219,0.0004850763,0.0004648319,0.0007170751,0.0006067346],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004809214,"about_ca_system_score_gemma":0.0003924654,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000656421,"about_ca_topic_score_gemma":0.0007482925,"domain_scores_codex":[0.9990318,0.0004208317,0.00009829851,0.0001232894,0.000267026,0.0000589001],"domain_scores_gemma":[0.9988229,0.0005833392,0.0002705634,0.00005160371,0.0002234631,0.00004813363],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.005125028,0.000617098,0.03084809,0.009472513,0.002538623,0.001835471,0.0002336778,0.002225736,0.1508903,0.006417615,0.006884919,0.7829109],"study_design_scores_gemma":[0.0007927836,0.01574319,0.28685,0.003244571,0.007510237,0.01359691,0.0005397109,0.004722557,0.2063151,0.01901915,0.4414495,0.0002162024],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.2075522,0.7528551,0.00517481,0.004191006,0.0006195937,0.0001092222,0.001278874,0.0001539995,0.02806522],"genre_scores_gemma":[0.7190092,0.2687545,0.002829969,0.001830457,0.0005148928,0.00006890733,0.0006662706,0.00005188572,0.006273995],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.003559981,"threshold_uncertainty_score":0.01190931,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05744669577431517,"score_gpt":0.4507032315356542,"score_spread":0.393256535761339,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}