{"id":"W7154993079","doi":"10.1093/skinhd/vzaf106","title":"Two inflammasomes as tumour markers for nonmelanocytic skin cancer: new hopes for early detection and targeted therapy","year":2025,"lang":"en","type":"article","venue":"Skin Health and Disease","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"","keywords":"Inflammasome; Context (archaeology); Skin cancer; Targeted therapy; NLRP1; Basal cell carcinoma; Cancer; Melanoma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002660414,0.0006552088,0.002227542,0.003123055,0.0003582426,0.002839249,0.0007164208,0.002472406,0.003925661],"category_scores_gemma":[0.003264587,0.0002812055,0.001551469,0.00241165,0.00101607,0.005235192,0.001048957,0.00255766,0.000977934],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001181211,"about_ca_system_score_gemma":0.00211838,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005131297,"about_ca_topic_score_gemma":0.0008338018,"domain_scores_codex":[0.9992471,0.0002183945,0.0001560661,0.00009978946,0.0002154803,0.00006329601],"domain_scores_gemma":[0.9962858,0.001923579,0.0006800421,0.00008429425,0.000870969,0.0001553093],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.001276231,0.0002728681,0.003395593,0.1198376,0.0007573391,0.002495724,0.0006066379,0.0003839988,0.01302436,0.02083492,0.03467434,0.8024405],"study_design_scores_gemma":[0.0004284595,0.0017929,0.01758031,0.06772384,0.002738912,0.01053148,0.002371158,0.001310094,0.007101466,0.04520768,0.842935,0.0002787197],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.0005491032,0.9955017,0.0002653987,0.002685826,0.000504112,0.000008401271,0.00002242262,0.000008043382,0.000454932],"genre_scores_gemma":[0.01015815,0.9835649,0.001228093,0.002451006,0.001653808,0.00004114389,0.00007178147,0.000005350677,0.0008257731],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.003925661,"threshold_uncertainty_score":0.01406974,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006310421662022442,"score_gpt":0.2843202086393603,"score_spread":0.2780097869773379,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}