{"id":"W7162031722","doi":"10.82308/46313","title":"Abnormal placental DNA methylation and gene expression associated with assisted reproduction: early detection and effect of folic acid supplementation","year":2022,"lang":"en","type":"dissertation","venue":"","topic":"Prenatal Screening and Diagnostics","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Folic acid; Chromosome abnormality; Gene; Gene expression","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001901709,0.000189621,0.0002235291,0.0005008044,0.0004107379,0.0003541597,0.0002702601,0.0003008667,0.00182032],"category_scores_gemma":[0.0006046564,0.0001744257,0.0001869215,0.0006747504,0.0003240062,0.00008517008,0.0001522557,0.0003022481,0.0001139032],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002971665,"about_ca_system_score_gemma":0.002263302,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.5447296,"about_ca_topic_score_gemma":0.6188756,"domain_scores_codex":[0.9998202,0.00002766359,0.000004174176,0.00004512644,0.00006869716,0.00003422953],"domain_scores_gemma":[0.9997855,0.00003360429,0.00005063409,0.00001144657,0.0000688294,0.00004996779],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002952424,0.0001584253,0.5768253,0.0002381062,0.0001776697,0.001196921,0.002040078,0.0003452969,0.361061,0.0003171111,0.0006231904,0.05406458],"study_design_scores_gemma":[0.00001271754,0.0002731602,0.9832515,0.00001369174,0.00004145479,0.0004774308,0.0003911359,0.0002579288,0.01319166,0.00004135292,0.002038202,0.000009768317],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941142,0.002863433,0.0006234623,0.0001903054,0.000007630743,0.00002099092,0.000491406,0.00002001896,0.001668643],"genre_scores_gemma":[0.9940956,0.001263985,0.000793025,0.00007249467,0.000003070799,0.00001276331,0.0002229746,0.000005718774,0.003530408],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5447296,"threshold_uncertainty_score":0.9159032,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00901325319904641,"score_gpt":0.2720476439753166,"score_spread":0.2630343907762702,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}