{"id":"W7163904772","doi":"10.2196/84625","title":"Point-of-Care Nucleic Acid Tests (POC NATs) for HIV Testing and Viral Load Monitoring: A longitudinal, prospective study with randomized-controlled trial, qualitative, and systems engineering components to assess feasibility, acceptability, and test performance of POC NAT in the United States (Preprint)","year":2025,"lang":"en","type":"article","venue":"JMIR Research Protocols","topic":"SARS-CoV-2 detection and testing","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"","keywords":"Viral load; Human immunodeficiency virus (HIV); Prospective cohort study; Test (biology); Nucleic acid; Test strategy","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.03795037,0.001916529,0.001943056,0.0008697668,0.002153058,0.001644118,0.001418386,0.002470885,0.003664913],"category_scores_gemma":[0.04328746,0.001491999,0.002584392,0.001062859,0.003479732,0.002968864,0.00159415,0.003006764,0.0006954501],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002488177,"about_ca_system_score_gemma":0.007064003,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004598253,"about_ca_topic_score_gemma":0.006015847,"domain_scores_codex":[0.954909,0.03468669,0.002881664,0.003086268,0.002949269,0.001487004],"domain_scores_gemma":[0.9663271,0.01675466,0.007670046,0.00326725,0.00355754,0.002423362],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8315488,0.1021337,0.03459136,0.0007629595,0.002526771,0.00004200621,0.001389148,0.0005123684,0.001351947,0.0004820495,0.001080906,0.02357805],"study_design_scores_gemma":[0.4959251,0.4674165,0.03067337,0.0001702662,0.001534687,0.00003335381,0.0005477006,0.001100743,0.001263696,0.0004858353,0.0007773972,0.00007147158],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"protocol","genre_scores_codex":[0.9786648,0.0004767313,0.002515251,0.0002843659,0.0002756787,0.01647948,0.0005578356,0.00006814194,0.0006776846],"genre_scores_gemma":[0.9495748,0.000326296,0.01101999,0.0008396041,0.0002427584,0.03662162,0.0005483155,0.0000276935,0.0007989668],"genre_candidate":"protocol","genre_consensus":null,"teacher_disagreement_score":0.03795037,"threshold_uncertainty_score":0.2007032,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2239729681947861,"score_gpt":0.5142883387288929,"score_spread":0.2903153705341068,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}