{"id":"W7164230544","doi":"10.5376/pgt.2025.16.0028","title":"Advances in Saikosaponin Biosynthetic Pathways and Gene Regulation in Bupleurum (Bupleurum chinense)","year":2025,"lang":"","type":"article","venue":"Plant Gene and Trait","topic":"Plant biochemistry and biosynthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Metabolic engineering; Metabolic pathway; Transcriptional regulation; Transcription factor; Regulation of gene expression; Gene; Triterpene; Mechanism (biology); Regulator gene","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000178568,0.0004437839,0.0003358515,0.00069076,0.0002955922,0.0005082038,0.0001824515,0.00027002,0.0006046941],"category_scores_gemma":[0.0001040292,0.0001390512,0.0004142577,0.0006914644,0.0001933787,0.0008850152,0.000374379,0.000575642,0.0002202602],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000419909,"about_ca_system_score_gemma":0.0003527694,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008870431,"about_ca_topic_score_gemma":0.001023717,"domain_scores_codex":[0.9999142,0.000008657789,0.000009807529,0.00003737225,0.00002137392,0.000008638136],"domain_scores_gemma":[0.9999101,0.0000186002,0.00002999172,0.000006917859,0.00001866093,0.00001565293],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001515753,0.00002121073,0.002131729,0.001156449,0.00002754808,0.0003350432,0.0002471704,0.0006716261,0.9104686,0.001962892,0.000246559,0.08257944],"study_design_scores_gemma":[0.00003242732,0.000685388,0.1223857,0.0003563528,0.0004902479,0.004238111,0.001065433,0.005664714,0.5642652,0.00974017,0.2909243,0.0001520904],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5421869,0.363793,0.06345382,0.00282445,0.0002655474,0.00009365379,0.002380927,0.0007158726,0.02428584],"genre_scores_gemma":[0.7690811,0.1778829,0.03832901,0.0005374248,0.0001873116,0.00008417221,0.003353003,0.00009792647,0.01044714],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008870431,"threshold_uncertainty_score":0.003046691,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005471526229892557,"score_gpt":0.2014128460012569,"score_spread":0.1959413197713643,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}