{"id":"W7261346","doi":"10.1007/978-3-642-31659-3_3","title":"Cancer-Associated Perturbations in Alternative Pre-messenger RNA Splicing","year":2013,"lang":"en","type":"review","venue":"Cancer treatment and research","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"RNA splicing; Intron; Alternative splicing; Biology; Minigene; Spliceosome; Exonic splicing enhancer; Exon; Splicing factor; Genetics; Minor spliceosome; snRNP; Precursor mRNA; Gene; Computational biology; RNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005277264,0.0007789388,0.001122687,0.001116332,0.0001837404,0.0007899939,0.0006559927,0.0007963004,0.001684763],"category_scores_gemma":[0.0005531202,0.000252275,0.0003174567,0.00146468,0.000536785,0.0006704042,0.0005462674,0.001292837,0.001214483],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005915307,"about_ca_system_score_gemma":0.000768111,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005938236,"about_ca_topic_score_gemma":0.001493768,"domain_scores_codex":[0.9998534,0.00001887691,0.0000206176,0.00003232394,0.00005750611,0.00001738716],"domain_scores_gemma":[0.9997857,0.0001056041,0.00003267326,0.000008415293,0.00005200549,0.00001570745],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009083591,0.00004475897,0.0002396912,0.008389823,0.00006269396,0.0002687588,0.00002433879,0.0004464304,0.006733452,0.003760836,0.01772789,0.9622105],"study_design_scores_gemma":[0.00002009331,0.00009196479,0.00100878,0.001460784,0.0001492847,0.001789641,0.00004975377,0.0002081048,0.005698971,0.003991302,0.9855053,0.0000259905],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002458299,0.997489,0.0005111978,0.0002843769,0.0002515058,0.000004819336,0.00003242825,0.000013851,0.00116696],"genre_scores_gemma":[0.001402963,0.9970617,0.0004131588,0.0001874069,0.0001792882,0.000007655719,0.0000491074,0.000002652805,0.0006961886],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001684763,"threshold_uncertainty_score":0.005636096,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.11403409843813,"score_gpt":0.4620501970553664,"score_spread":0.3480160986172364,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}