{"id":"W73112114","doi":"10.1161/circ.118.suppl_18.s_642-b","title":"Abstract 1066: Ultrasound-targeted Plasmid Delivery of Vascular Endothelial Growth Factor and Angiopoietin-1: Combination Gene Therapy for Therapeutic Angiogenesis","year":2008,"lang":"en","type":"article","venue":"Circulation","topic":"Ultrasound and Hyperthermia Applications","field":"Engineering","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital","funders":"","keywords":"Medicine; Angiogenesis; Ligation; Therapeutic angiogenesis; Vascular endothelial growth factor; Neovascularization; Angiopoietin; Microbubbles; Arteriogenesis; Ischemia; Genetic enhancement; Gene delivery; Vascular endothelial growth factor A; Internal medicine; Ultrasound; Endocrinology; Urology; VEGF receptors; Biology; Gene; Radiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001323019,0.0003942092,0.0004264188,0.0003261219,0.00007555084,0.000180549,0.0001890215,0.0003147745,0.002097229],"category_scores_gemma":[0.00009087785,0.0001176468,0.0002546007,0.0002275359,0.0001591782,0.0002320813,0.0001863608,0.0005013843,0.0004557847],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001823969,"about_ca_system_score_gemma":0.0001530559,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002490653,"about_ca_topic_score_gemma":0.0002600694,"domain_scores_codex":[0.9998981,0.00001366484,0.000006953526,0.00002046921,0.00003991325,0.00002094949],"domain_scores_gemma":[0.9999447,0.000006174922,0.00002051873,0.000003518801,0.000005936564,0.00001920373],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000378145,0.000156232,0.0001235072,0.00008766097,0.000009900845,0.00003936964,0.000009817005,0.0001621032,0.9925564,0.0001050704,0.000153264,0.006218554],"study_design_scores_gemma":[0.0000985709,0.002911799,0.001627422,0.00001179348,0.00004147946,0.0003381404,0.000006937932,0.001727766,0.9895567,0.00004496703,0.003626847,0.000007396195],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9760666,0.003772531,0.01623195,0.0002168689,0.0001571773,0.0001353683,0.0003220695,0.0002637079,0.002833702],"genre_scores_gemma":[0.9794782,0.002226847,0.01042231,0.00007080529,0.00006294106,0.0001337945,0.000391599,0.00002904829,0.007184411],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002097229,"threshold_uncertainty_score":0.007015884,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01772218921628262,"score_gpt":0.2057526651243705,"score_spread":0.1880304759080878,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}