{"id":"W745603684","doi":"10.1007/978-3-319-17305-4_5","title":"Aptamers in Oncotherapy","year":2015,"lang":"en","type":"book-chapter","venue":"RNA technologies","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Aptamer; Oncolytic virus; Oligonucleotide; Computational biology; Biology; Nanotechnology; Virology; Virus; Molecular biology; DNA; Biochemistry; Materials science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001387357,0.000334409,0.0003633108,0.0002619573,0.00002675914,0.00001410212,0.0003654428,0.001108354,0.000003750398],"category_scores_gemma":[0.00006818938,0.0002920142,0.0001468634,0.00005721652,0.0003290451,0.000002146025,0.0001903819,0.0003384579,0.00001217125],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007214549,"about_ca_system_score_gemma":0.00006852864,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006043348,"about_ca_topic_score_gemma":0.00007526976,"domain_scores_codex":[0.9988205,0.000008177544,0.0002636411,0.0005099184,0.0001633519,0.0002343451],"domain_scores_gemma":[0.9990144,0.000005935543,0.0001765928,0.0006892421,0.00008865036,0.00002523056],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001623136,0.00006696166,0.00009242649,0.00003836503,0.000324719,0.0001074585,0.00001558012,0.000006760446,0.347951,0.01648495,0.04986851,0.5848809],"study_design_scores_gemma":[0.0001986844,0.000259462,0.000002374188,0.00008899159,0.00002192946,0.00001185133,0.00006882165,0.00000351952,0.2039417,0.02505822,0.7698759,0.0004685514],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.008036852,0.02593667,0.0007923931,0.002228625,0.0002934091,0.0009421787,0.0001477189,0.002553487,0.9590687],"genre_scores_gemma":[0.4392264,0.02869875,0.01253608,0.0002668689,0.0002365688,0.00003399863,0.0003470102,0.0002000307,0.5184543],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.7200074,"threshold_uncertainty_score":0.9999532,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02459089731006916,"score_gpt":0.2850512992573968,"score_spread":0.2604604019473277,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}