{"id":"W753158220","doi":"10.1007/s10620-015-3797-3","title":"Trimethylamine-N-oxide: A Novel Biomarker for the Identification of Inflammatory Bowel Disease","year":2015,"lang":"en","type":"article","venue":"Digestive Diseases and Sciences","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":95,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Trimethylamine N-oxide; Inflammatory bowel disease; Biomarker; Ulcerative colitis; Population; Microbiome; Dysbiosis; Internal medicine; Crohn's disease; Choline; Gut flora; Trimethylamine; Medicine; Immunology; Disease; Gastroenterology; Chemistry; Biology; Bioinformatics; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004323802,0.0004203209,0.0004259985,0.0009857401,0.000309515,0.0005249137,0.0005183879,0.001128195,0.000874461],"category_scores_gemma":[0.0006582767,0.0001836924,0.0002891636,0.0004510197,0.0003281557,0.0004289655,0.0004063774,0.0006308835,0.0003234294],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002992238,"about_ca_system_score_gemma":0.000303488,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009862328,"about_ca_topic_score_gemma":0.001575399,"domain_scores_codex":[0.9997419,0.00005880312,0.00001918792,0.00007194595,0.00006553165,0.00004269968],"domain_scores_gemma":[0.9996265,0.00006056429,0.0001249619,0.00002076112,0.00007513642,0.00009194194],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003198873,0.000312168,0.1533091,0.0004390774,0.0004105896,0.002069133,0.0002181039,0.0001472363,0.8001192,0.0002926828,0.0006546472,0.03882913],"study_design_scores_gemma":[0.0001971154,0.005103181,0.4216405,0.000234274,0.0009040016,0.0201604,0.0006476301,0.006691482,0.5308884,0.001417513,0.01201353,0.000102025],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9669668,0.02321988,0.005367265,0.0004570568,0.0002145679,0.00007908094,0.0008489536,0.0001327181,0.002713687],"genre_scores_gemma":[0.9866874,0.003416579,0.006606224,0.000338825,0.0001266593,0.00006206753,0.0006440018,0.0000159135,0.002102233],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001128195,"threshold_uncertainty_score":0.002925336,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03597467802157869,"score_gpt":0.3165353411024058,"score_spread":0.2805606630808271,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}