{"id":"W760715003","doi":"10.1016/j.bcp.2015.06.019","title":"From B.Sc. to Ph.D., my shuffle off to Buffalo","year":2015,"lang":"en","type":"review","venue":"Biochemical Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"Nucro Technics","funders":"","keywords":"Muscarinic acetylcholine receptor; Tachyphylaxis; Chemistry; Contraction (grammar); Depolarization; Neuroscience; Pharmacology; Medicine; Receptor; Internal medicine; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0003204151,0.0007019365,0.001470287,0.0001446451,0.00006221674,0.00003719726,0.000988742,0.00109685,0.001203572],"category_scores_gemma":[0.0001224264,0.0006392887,0.0005034384,0.0002891036,0.00006300474,0.000002867711,0.0008512028,0.0004125297,0.001031777],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001364751,"about_ca_system_score_gemma":0.0004480064,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004369774,"about_ca_topic_score_gemma":0.000001270336,"domain_scores_codex":[0.9967384,0.0002207185,0.0007032394,0.001339144,0.0002722025,0.0007262392],"domain_scores_gemma":[0.9980788,0.00005116543,0.0001941791,0.0005626329,0.0001790361,0.0009341741],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005545866,0.00006711444,7.008295e-8,0.0001931443,0.0001908855,0.000009269394,0.00001944188,0.000001626971,0.332196,0.00000310818,0.5370836,0.1301803],"study_design_scores_gemma":[0.0003070607,0.000260541,4.832735e-8,0.000270474,0.0003738532,0.00001209193,0.000008850596,0.000001449504,0.1962078,0.0000304828,0.8019263,0.0006010968],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002176457,0.9930778,0.0003246829,0.0001691764,0.00211995,0.001146245,0.0003976749,0.00004712334,0.0005408928],"genre_scores_gemma":[0.0003071309,0.9846631,0.00229713,0.002501346,0.006480571,0.0005008559,0.001831663,0.0001709611,0.001247192],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.2648427,"threshold_uncertainty_score":0.999746,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04395937114015567,"score_gpt":0.3743621040463773,"score_spread":0.3304027329062216,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}