{"id":"W760715003","doi":"10.1016/j.bcp.2015.06.019","title":"From B.Sc. to Ph.D., my shuffle off to Buffalo","year":2015,"lang":"en","type":"review","venue":"Biochemical Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"Nucro Technics","funders":"","keywords":"Muscarinic acetylcholine receptor; Tachyphylaxis; Chemistry; Contraction (grammar); Depolarization; Neuroscience; Pharmacology; Medicine; Receptor; Internal medicine; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004762645,0.0006877565,0.0005918231,0.000802698,0.0003694542,0.001082395,0.00072579,0.001029543,0.1045044],"category_scores_gemma":[0.0008410737,0.00021179,0.0003216162,0.0007561831,0.0005814665,0.0009532016,0.001381786,0.002295119,0.07123614],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006719349,"about_ca_system_score_gemma":0.001072088,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007478469,"about_ca_topic_score_gemma":0.001785165,"domain_scores_codex":[0.9998261,0.00001879359,0.000009478931,0.00004152897,0.00006849164,0.00003552889],"domain_scores_gemma":[0.9996116,0.00006241191,0.00002495175,0.00001475509,0.0001021137,0.0001842172],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001962134,0.00006624124,0.0001744555,0.001229897,0.00001939639,0.0001785284,0.00004363672,0.000154884,0.00182188,0.004493841,0.2865524,0.7050686],"study_design_scores_gemma":[0.000009428206,0.00005003609,0.0003344647,0.0004098715,0.00000642055,0.0003868002,0.00001520361,0.00002296221,0.0003022496,0.001006442,0.9974515,0.000004558934],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"commentary","genre_scores_codex":[0.001123165,0.8418689,0.001780723,0.02161159,0.01464702,0.00005745675,0.0004113035,0.0002532134,0.1182465],"genre_scores_gemma":[0.008517605,0.6543053,0.001239227,0.004733368,0.003973313,0.00007171431,0.0004571295,0.00008121818,0.3266211],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.1045044,"threshold_uncertainty_score":0.349602,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04395937114015567,"score_gpt":0.3743621040463773,"score_spread":0.3304027329062216,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}