{"id":"W762283860","doi":"10.1139/o08-117","title":"Transcriptional and epigenetic functions of histone variant H2A.ZThis paper is one of a selection of papers published in this Special Issue, entitled CSBMCB’s 51st Annual Meeting – Epigenetics and Chromatin Dynamics, and has undergone the Journal’s usual peer review process.","year":2009,"lang":"en","type":"review","venue":"Biochemistry and Cell Biology","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Ontario Institute for Cancer Research","funders":"National Cancer Institute; Canada Research Chairs","keywords":"Epigenetics; Chromatin; Histone; Biology; Epigenomics; Genetics; Histone code; Histone H2A; Histone-modifying enzymes; Chromatin remodeling; Computational biology; Gene; Cell biology; Gene expression; Nucleosome; DNA methylation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007493434,0.0003471647,0.0009839336,0.00007863675,0.0001154095,0.00002073595,0.0001748989,0.0005655083,0.0007007153],"category_scores_gemma":[0.0001562571,0.0002836048,0.0001308315,0.0001623448,0.0005438309,0.000007701226,0.00008990682,0.0002954676,1.979853e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003658855,"about_ca_system_score_gemma":0.0003262132,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003825873,"about_ca_topic_score_gemma":0.00007342691,"domain_scores_codex":[0.9980106,0.0001752141,0.0009750187,0.0004515662,0.0001667484,0.0002207958],"domain_scores_gemma":[0.9985263,0.00005570922,0.0008061669,0.0002200911,0.0003028424,0.00008888125],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002537502,0.0009192856,0.00040474,0.07185588,0.001090784,0.00000483488,0.0008768227,0.0000100001,0.640786,0.00009759991,0.005135464,0.2785648],"study_design_scores_gemma":[0.003649756,0.002933049,0.0008099603,0.0141341,0.004839712,0.001139598,0.001294831,0.0003848776,0.05841877,0.0004873909,0.9098593,0.002048661],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02563922,0.9719126,0.00003847761,0.0003345434,0.00008613949,0.0003682393,0.0004636607,0.000002508961,0.00115463],"genre_scores_gemma":[0.02301424,0.9746895,0.0002964396,0.00005756707,0.0002644659,0.00001228694,0.0005387609,0.00002349189,0.001103232],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9047238,"threshold_uncertainty_score":0.9999616,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01206176462435439,"score_gpt":0.2599809384905329,"score_spread":0.2479191738661785,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}