{"id":"W76562646","doi":"10.1096/fasebj.24.1_supplement.lb594","title":"Differential calcineurin/NFATc1‐c3 signaling in the regulation of the skeletal muscle fiber phenotype","year":2010,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Concordia University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"NFAT; Gene isoform; Biology; Phenotype; Transcription factor; Skeletal muscle; Calcineurin; Cell biology; Gene expression; Transgene; Regulation of gene expression; Gene; Genetics; Internal medicine; Endocrinology; Transplantation; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002771541,0.0004164415,0.000183071,0.0003033243,0.0002668328,0.0003052788,0.0002605432,0.0003318242,0.001167696],"category_scores_gemma":[0.0001354178,0.0001544977,0.0002511906,0.0001726685,0.0005107239,0.0002889858,0.000219295,0.0004823644,0.0001714396],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005685111,"about_ca_system_score_gemma":0.0004902509,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002330484,"about_ca_topic_score_gemma":0.005872062,"domain_scores_codex":[0.9997844,0.00002544947,0.00001753457,0.00005813986,0.00006410009,0.00005035652],"domain_scores_gemma":[0.9998394,0.00002250066,0.00003733843,0.000018494,0.00002128513,0.00006088351],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007654261,0.000008204453,0.0004084601,0.00001152625,0.000001645787,0.00002199719,0.000008336302,0.00001937842,0.9990012,0.00003774901,0.000004389517,0.0004005344],"study_design_scores_gemma":[0.00003295805,0.0002230593,0.05849128,0.00001109342,0.00002716128,0.0004978127,0.00006996656,0.00123664,0.9385288,0.0001494767,0.0007238226,0.000007883972],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964151,0.0009715474,0.001579701,0.00006352738,0.00001032079,0.00001350783,0.0001708341,0.00002970846,0.0007457368],"genre_scores_gemma":[0.9970134,0.0003661724,0.0009862463,0.00002484028,0.000003134363,0.00001954072,0.0001522597,0.00001196205,0.001422462],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002330484,"threshold_uncertainty_score":0.004633844,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01050108058747752,"score_gpt":0.2377254291902551,"score_spread":0.2272243486027776,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}