{"id":"W76899857","doi":"10.1007/978-1-59745-035-5_13","title":"Metallothioneins in Drug Resistance","year":2007,"lang":"en","type":"book-chapter","venue":"Humana Press eBooks","topic":"Trace Elements in Health","field":"Nursing","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Occupational Cancer Research Centre","funders":"","keywords":"Transcription factor; Cell biology; Metallothionein; Biology; Transcription (linguistics); Signal transduction; Gene expression; Downregulation and upregulation; Chemistry; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006978931,0.0005553234,0.0007085158,0.0004491147,0.0001770611,0.00006365997,0.0005817072,0.0004331653,0.0002205278],"category_scores_gemma":[0.00002289773,0.0006306065,0.0001731131,0.00000958219,0.0001922516,0.00007249141,0.0001348752,0.001266692,0.00007114035],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004978699,"about_ca_system_score_gemma":0.00004662198,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005479972,"about_ca_topic_score_gemma":0.02404915,"domain_scores_codex":[0.9967311,0.00006855172,0.0009614354,0.0008072294,0.0007301178,0.0007015384],"domain_scores_gemma":[0.9980723,0.0001783359,0.0004682328,0.001049166,0.00007853829,0.0001534135],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003750197,0.00004711373,0.000001777646,0.0008000482,0.0001022392,0.0003161454,0.002377322,0.000004347457,0.00001457624,0.9229328,0.0247082,0.04832039],"study_design_scores_gemma":[0.0005910919,0.00002978703,0.00003710586,0.0008408886,0.00009038647,0.000003123137,0.000009754321,0.00000239119,0.0003087073,0.01664357,0.9808897,0.0005534538],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.00007583275,0.01158756,0.00002366932,0.00007631599,0.001534593,0.001060922,0.00003699534,0.0002492298,0.9853549],"genre_scores_gemma":[0.003691656,0.0001800632,0.001311138,0.0006469184,0.0005310843,0.0000433899,0.00003134785,0.0002537383,0.9933107],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.9561815,"threshold_uncertainty_score":0.9996145,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1164202824535488,"score_gpt":0.3377940175570153,"score_spread":0.2213737351034665,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}