{"id":"W770860555","doi":"10.1016/j.mce.2015.06.019","title":"Human somatostatin receptor-3 distinctively induces apoptosis in MCF-7 and cell cycle arrest in MDA-MB-231 breast cancer cells","year":2015,"lang":"en","type":"article","venue":"Molecular and Cellular Endocrinology","topic":"Neuroendocrine Tumor Research Advances","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Michael Smith Health Research BC","keywords":"Somatostatin receptor; Somatostatin; Biology; Apoptosis; Cancer research; MCF-7; Endocrinology; Cytotoxic T cell; Cell cycle checkpoint; Internal medicine; Transfection; Cell growth; Cell cycle; Cancer cell; PI3K/AKT/mTOR pathway; Cancer; Cell culture; In vitro; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007170803,0.0001944763,0.0002543457,0.0002373016,0.0001597801,0.0002311311,0.0001067247,0.0002123123,0.001166278],"category_scores_gemma":[0.00009152506,0.0001020048,0.0003018185,0.0002181988,0.0001482456,0.0001187449,0.00009386424,0.0003700562,0.000360181],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003720527,"about_ca_system_score_gemma":0.0002732127,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002234337,"about_ca_topic_score_gemma":0.003380837,"domain_scores_codex":[0.9998956,0.00001192237,0.000009534341,0.00001220442,0.00002969294,0.00004109633],"domain_scores_gemma":[0.9999485,0.00001385687,0.000007215781,0.000008468805,0.000009146375,0.00001269006],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003228147,0.00005032028,0.0004808104,0.00002976199,0.000008537671,0.0001558064,0.00003263405,0.00005002806,0.9972163,0.0001013353,0.0001620548,0.001389484],"study_design_scores_gemma":[0.00005251544,0.0006997419,0.02017351,0.000006217712,0.0000322378,0.0008873326,0.0001258368,0.0006432225,0.9725621,0.00007971099,0.004729241,0.000008299978],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941439,0.002148725,0.0004626742,0.000183954,0.00006033076,0.00002226275,0.0006939318,0.00003375154,0.002250494],"genre_scores_gemma":[0.9944193,0.00112377,0.0004261567,0.0001208861,0.00001326918,0.00003023093,0.001292414,0.000007706618,0.002566278],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002234337,"threshold_uncertainty_score":0.004442692,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0164633678314161,"score_gpt":0.2882561470606426,"score_spread":0.2717927792292265,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}