{"id":"W770860555","doi":"10.1016/j.mce.2015.06.019","title":"Human somatostatin receptor-3 distinctively induces apoptosis in MCF-7 and cell cycle arrest in MDA-MB-231 breast cancer cells","year":2015,"lang":"en","type":"article","venue":"Molecular and Cellular Endocrinology","topic":"Neuroendocrine Tumor Research Advances","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Michael Smith Health Research BC","keywords":"Somatostatin receptor; Somatostatin; Biology; Apoptosis; Cancer research; MCF-7; Endocrinology; Cytotoxic T cell; Cell cycle checkpoint; Internal medicine; Transfection; Cell growth; Cell cycle; Cancer cell; PI3K/AKT/mTOR pathway; Cancer; Cell culture; In vitro; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001132277,0.0003186942,0.0005447116,0.000385984,0.00006336197,0.00003379084,0.0001545658,0.00004090562,0.00006094639],"category_scores_gemma":[0.00005354788,0.0003093014,0.00004957637,0.0003197261,0.0003348938,0.0001181372,0.000246606,0.0005726948,0.00001782817],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001076987,"about_ca_system_score_gemma":0.0001128088,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001755646,"about_ca_topic_score_gemma":0.0002888517,"domain_scores_codex":[0.9974784,0.0002731456,0.0003974,0.0006946807,0.0003060647,0.0008503115],"domain_scores_gemma":[0.9991056,0.00005086048,0.00009784724,0.000292973,0.00007843983,0.0003742239],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002203464,0.0003666142,0.05229418,0.0001802718,0.00002632708,0.004228631,0.0002688736,0.00003569097,0.9402449,0.0002761715,0.0001507938,0.001707205],"study_design_scores_gemma":[0.005418928,0.0004691331,0.01773593,0.0001027754,0.00003708321,0.0004812631,0.001027863,0.00007661156,0.9727607,0.0006430934,0.0008635928,0.0003830649],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944711,0.002283392,0.00002264681,0.001208292,0.0001340898,0.0005365749,0.00003722988,0.00004396729,0.001262656],"genre_scores_gemma":[0.9988356,0.0002548522,0.0002432587,0.0002022612,0.00004650227,0.0001274522,0.0000260479,0.00005163174,0.0002123774],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03455825,"threshold_uncertainty_score":0.9999359,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0164633678314161,"score_gpt":0.2882561470606426,"score_spread":0.2717927792292265,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}