{"id":"W774911715","doi":"","title":"P23H-Light Induced Retinal Degeneration occurs via cell death with autophagy in a Xenopus laevis Model of Retinitis Pigmentosa","year":2013,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Retinitis pigmentosa; Xenopus; Retinal degeneration; Autophagy; Degeneration (medical); Gene therapy of the human retina; Retinal; Programmed cell death; Ophthalmology; Medicine; Biology; Anatomy; Genetics; Apoptosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004087916,0.0006673179,0.0004930868,0.001342309,0.0007300193,0.0007000977,0.0005978206,0.001011304,0.003255103],"category_scores_gemma":[0.0001445803,0.0004513674,0.0008514686,0.0004309223,0.0008977451,0.0007445248,0.0003433778,0.001749838,0.0008180368],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009000538,"about_ca_system_score_gemma":0.000556016,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003501533,"about_ca_topic_score_gemma":0.004413014,"domain_scores_codex":[0.9995061,0.0001035746,0.00007508311,0.0001022124,0.0001102185,0.0001028348],"domain_scores_gemma":[0.9996752,0.0000469413,0.0001181478,0.00004932842,0.00002419938,0.00008628049],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004447644,0.0001058341,0.0001290573,0.00004824722,0.00001501561,0.0003213429,0.0000607461,0.00008620285,0.9978636,0.0003885914,0.00007505343,0.0004615158],"study_design_scores_gemma":[0.00007161314,0.0003677724,0.001994011,0.00001055055,0.00002889688,0.0004061197,0.00009047951,0.000498917,0.9952444,0.00008272626,0.001192314,0.00001206921],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922174,0.001363957,0.002030403,0.0003861414,0.0001079709,0.0000797453,0.001059878,0.0001890521,0.002565415],"genre_scores_gemma":[0.9842552,0.001154686,0.002405778,0.00008351089,0.00002199968,0.0001721145,0.0005362328,0.00008047433,0.01129011],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003501533,"threshold_uncertainty_score":0.01088941,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02649772211245119,"score_gpt":0.2846126722583408,"score_spread":0.2581149501458896,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}