{"id":"W77500779","doi":"10.1182/blood.v95.1.102","title":"Expansion of human cord blood CD34+CD38−cells in ex vivo culture during retroviral transduction without a corresponding increase in SCID repopulating cell (SRC) frequency: dissociation of SRC phenotype and function","year":2000,"lang":"en","type":"article","venue":"Blood","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":251,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; Hospital for Sick Children; University of Toronto","funders":"","keywords":"CD38; Stem cell; Biology; Haematopoiesis; CD34; Cord blood; Cell biology; Molecular biology; Population; Ex vivo; Immunology; Medicine; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003812539,0.0004398134,0.0004246692,0.0003100123,0.0001735076,0.0004370208,0.0003999452,0.0002844973,0.002658579],"category_scores_gemma":[0.0001505344,0.0001542986,0.0002916391,0.0003332136,0.0001790073,0.0001908057,0.0004153277,0.000830576,0.001764415],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002448808,"about_ca_system_score_gemma":0.0002446225,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007480301,"about_ca_topic_score_gemma":0.000934674,"domain_scores_codex":[0.9996533,0.00004115991,0.00004889458,0.00006465716,0.0001463624,0.00004567977],"domain_scores_gemma":[0.9998142,0.00002689557,0.00002897142,0.00005589178,0.00003202905,0.00004198955],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004236123,0.0000317531,0.0001132487,0.0000205521,0.000001885029,0.00002940919,0.00002854779,0.00003449331,0.9979964,0.0000462406,0.0000468783,0.001608193],"study_design_scores_gemma":[0.00001170062,0.000215748,0.001636413,0.000007106745,0.00001155703,0.0002524042,0.000007264995,0.0005155307,0.99385,0.00001351596,0.003476018,0.000002658759],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9646425,0.002186078,0.02522885,0.0001309498,0.00006438207,0.0005554085,0.002046761,0.0003914226,0.004753586],"genre_scores_gemma":[0.9356851,0.002630411,0.04267616,0.0001199996,0.0000589363,0.0005792124,0.006385842,0.000170752,0.01169352],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002658579,"threshold_uncertainty_score":0.008893847,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009587674266420888,"score_gpt":0.2434874860283694,"score_spread":0.2338998117619486,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}