{"id":"W77881891","doi":"10.1007/7854_2014_353","title":"Neurobiology of Huntington’s Disease","year":2014,"lang":"en","type":"review","venue":"Current topics in behavioral neurosciences","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":14,"is_retracted":false,"has_abstract":false,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"","keywords":"Huntington's disease; Disease; Neuroscience; Trinucleotide repeat expansion; Genetics; Hereditary Diseases; Gene; Huntingtin; Biology; Medicine; Allele; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000198938,0.000602838,0.001482242,0.0005584289,0.0001268698,0.00008665853,0.001722802,0.0001213947,0.0000346271],"category_scores_gemma":[0.00095893,0.0005000715,0.0005074401,0.00108949,0.0009483807,0.0001302416,0.0005031122,0.0006059698,0.00002806683],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003953525,"about_ca_system_score_gemma":0.000398585,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004840627,"about_ca_topic_score_gemma":0.000004339649,"domain_scores_codex":[0.9949699,0.001123103,0.001156295,0.001573764,0.0005400463,0.0006368826],"domain_scores_gemma":[0.9978171,0.0003287766,0.0007267513,0.000809106,0.00004523755,0.0002730115],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000007314589,0.001287013,0.002755455,0.006145911,8.098415e-7,0.00001308274,0.00003048006,0.00001987772,0.0007313188,0.001677025,0.0001340079,0.9871977],"study_design_scores_gemma":[0.0001908112,0.0002627804,0.001035975,0.002524002,0.0002339754,0.000003222432,0.000002718881,0.00001720178,0.0040097,0.0001631845,0.9908072,0.00074927],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1070585,0.8773606,0.00001328478,0.00004139614,0.01341273,0.001602718,0.0003035318,0.0001001066,0.0001071776],"genre_scores_gemma":[0.008018393,0.9913109,0.00001696555,0.0000613997,0.0002130216,0.000148315,0.00001569865,0.00004574255,0.0001695793],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9906731,"threshold_uncertainty_score":0.9997451,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1939691530469295,"score_gpt":0.4317566897744831,"score_spread":0.2377875367275536,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}