{"id":"W78744612","doi":"10.1182/blood.v95.11.3489","title":"Mice lacking flt3 ligand have deficient hematopoiesis affecting hematopoietic progenitor cells, dendritic cells, and natural killer cells","year":2000,"lang":"en","type":"article","venue":"Blood","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":882,"is_retracted":false,"has_abstract":true,"ca_institutions":"Research & Development Corporation","funders":"","keywords":"Haematopoiesis; Biology; Progenitor cell; Myeloid; Bone marrow; Spleen; CD11c; CD8; Immunology; Lymphopoiesis; Stem cell; Dendritic cell; Cell biology; Antigen","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0002332749,0.0003268255,0.0003582892,0.0001256792,0.0004692724,0.0001008124,0.0001657727,0.0002693772,0.001155621],"category_scores_gemma":[0.00002199908,0.0003065073,0.0001542074,0.0001267799,0.0001294027,0.0001618935,0.00007413619,0.0004964452,0.001337527],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003816904,"about_ca_system_score_gemma":0.00002872926,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006539575,"about_ca_topic_score_gemma":0.00001550161,"domain_scores_codex":[0.9982644,0.0002028858,0.0004075628,0.0005015854,0.00007750947,0.0005460851],"domain_scores_gemma":[0.9992868,0.0001895579,0.0001283921,0.0002761675,0.00007341447,0.00004569523],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006471812,0.0004689904,0.0001923438,0.0001136424,0.0001833758,0.00001697116,0.001299342,0.000009224388,0.993304,0.00001239159,0.003616256,0.0007188147],"study_design_scores_gemma":[0.001789059,0.0001343777,0.0001617253,0.0001193743,0.0002103773,0.0005580177,0.001441131,0.00002617394,0.9746739,0.00000748042,0.02052394,0.0003544028],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9856593,0.006603136,0.00001822223,0.00005656585,0.005661621,0.0003958814,0.000003319777,0.000150219,0.001451711],"genre_scores_gemma":[0.9748034,0.0002374849,0.0001281838,0.0001729283,0.00009134599,0.00002525483,0.0000305672,0.00004318081,0.02446761],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02301589,"threshold_uncertainty_score":0.9999387,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006408495738670238,"score_gpt":0.2070385583558723,"score_spread":0.200630062617202,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}