{"id":"W788047662","doi":"10.2196/resprot.4320","title":"Accuracy of Detecting Residual Disease After Cross Neoadjuvant Chemoradiotherapy for Esophageal Cancer (preSANO Trial): Rationale and Protocol","year":2015,"lang":"en","type":"article","venue":"JMIR Research Protocols","topic":"Esophageal Cancer Research and Treatment","field":"Medicine","cited_by":77,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Stichting Coolsingel; KWF Kankerbestrijding","keywords":"Medicine; Esophageal cancer; Esophagectomy; Esophagus; Neoadjuvant therapy; Chemoradiotherapy; Radiology; Adenocarcinoma; Cancer; Regimen; Surgery; Internal medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001966362,0.0002458226,0.000489275,0.0002455064,0.0002056634,0.0001732907,0.0002212492,0.0001138319,0.0002612251],"category_scores_gemma":[0.001362706,0.0001867887,0.0001275408,0.0003505425,0.0004195956,0.0003212571,0.0001580678,0.0004359517,0.000007604328],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004028754,"about_ca_system_score_gemma":0.002804676,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001074722,"about_ca_topic_score_gemma":0.00003094988,"domain_scores_codex":[0.9961748,0.0003354945,0.0005350142,0.0006068429,0.001557749,0.0007900652],"domain_scores_gemma":[0.9964362,0.000536144,0.0001668457,0.000576076,0.001282073,0.001002701],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.868557,0.002550174,0.06097643,0.006359769,0.0001909375,0.0004147075,0.0008968939,0.00001418139,0.001542002,0.0001431248,0.007836304,0.05051843],"study_design_scores_gemma":[0.6059383,0.03992561,0.07119905,0.005666847,0.00003719098,0.00003913172,0.000196136,0.0006888593,0.1035458,0.003599048,0.1684634,0.0007005556],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.0230306,0.0003058928,0.00002781964,0.0009400661,0.000007512728,0.9753749,0.0001700156,0.00004469573,0.00009843994],"genre_scores_gemma":[0.02534403,0.000003780612,0.0008523037,0.00006860585,0.000666358,0.9712799,0.00001842248,0.00006021631,0.001706442],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.2626187,"threshold_uncertainty_score":0.7617024,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2702804426200023,"score_gpt":0.5923795859597891,"score_spread":0.3220991433397868,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}