{"id":"W791739123","doi":"10.1139/y07-109","title":"Adjuvant activities of saponins from the root of Polygala senega L.This article is one of a selection of papers published in this special issue (part 2 of 2) on the Safety and Efficacy of Natural Health Products.","year":2007,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Natural product bioactivities and synthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; Health Canada","funders":"College of Pharmacy and Nutrition, University of Saskatchewan; Ministry of Agriculture - Saskatchewan","keywords":"Saponin; Adjuvant; Antigen; Biology; Pharmacology; Immunization; In vitro; Stimulation; Spleen; Traditional medicine; Immunology; Medicine; Biochemistry; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006701341,0.0001087289,0.0004927573,0.0001080651,0.00005045391,0.00000152418,0.000148685,0.0001064428,0.0009158935],"category_scores_gemma":[0.0001902333,0.00007282345,0.00007970269,0.0001584982,0.0007058561,0.00001319881,0.00002525072,0.0002504577,3.923368e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002206561,"about_ca_system_score_gemma":0.0004334173,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003939012,"about_ca_topic_score_gemma":0.004592075,"domain_scores_codex":[0.9987019,0.0003005157,0.0005636143,0.0001533238,0.00008690913,0.0001936828],"domain_scores_gemma":[0.9985707,0.0003120554,0.0007545289,0.0001237057,0.000169058,0.0000699402],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002130556,0.00009949931,0.003165149,0.00008260784,0.0002654134,5.727713e-7,0.001118926,0.00001276392,0.9868113,0.00005142353,0.002712674,0.003549142],"study_design_scores_gemma":[0.0006839182,0.0007799868,0.07666367,0.00004105812,0.00005230355,0.000006491184,0.0003229372,0.00000486957,0.9193994,0.00004573367,0.001947029,0.00005265008],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938473,0.00189826,5.187601e-7,0.003525475,0.0003182999,0.000153664,0.0001204353,3.638159e-7,0.000135715],"genre_scores_gemma":[0.9986233,0.0005531837,0.00003124302,0.0002563657,0.0004764737,5.4658e-7,0.000005839636,0.000005978683,0.00004707038],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07349852,"threshold_uncertainty_score":0.9999974,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008592842940953652,"score_gpt":0.243221342888556,"score_spread":0.2346284999476024,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}