{"id":"W79694754","doi":"10.1016/j.jcin.2014.06.014","title":"Direct Oral Anticoagulants","year":2014,"lang":"en","type":"review","venue":"JACC: Cardiovascular Interventions","topic":"Atrial Fibrillation Management and Outcomes","field":"Medicine","cited_by":110,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"Bayer HealthCare","keywords":"Rivaroxaban; Dabigatran; Medicine; Apixaban; Partial thromboplastin time; Warfarin; Atrial fibrillation; Prothrombin time; Pharmacodynamics; Direct thrombin inhibitor; Major bleeding; Intensive care medicine; Drug; Coagulation testing; Edoxaban; Coagulation; Internal medicine; Pharmacology; Pharmacokinetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","metaepi_broad","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001214604,0.0005073313,0.005078357,0.0005524438,0.0001261879,0.000094228,0.0002415831,0.0003264884,0.0005812995],"category_scores_gemma":[0.0003480835,0.0004009028,0.02534915,0.0005107283,0.00005799541,0.00008581491,0.0002150393,0.0003152514,0.001674481],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001374225,"about_ca_system_score_gemma":0.00007714008,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002929791,"about_ca_topic_score_gemma":0.000005743194,"domain_scores_codex":[0.9968227,0.0005039742,0.001097589,0.0006125139,0.0006025957,0.0003606],"domain_scores_gemma":[0.9979275,0.0001184206,0.0003009377,0.001369822,0.0001162687,0.0001670238],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000004897231,0.00001967743,0.0001024083,0.03371002,0.01713654,0.0000602744,0.000004726662,0.000005146596,3.46208e-8,0.0002232548,0.004961355,0.9437717],"study_design_scores_gemma":[0.0005825533,0.00006069001,0.0002145218,0.01871626,0.0329775,0.000110879,0.000004812139,0.000005463931,4.859608e-7,0.00001026107,0.9469662,0.0003503808],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000002235068,0.9821048,0.003132054,0.00004599194,0.001208869,0.001568233,0.00003643364,0.0002374359,0.01166389],"genre_scores_gemma":[0.00009077435,0.9854162,0.0004160636,0.00002448794,0.001644672,0.00004356399,0.0006091316,0.0001079334,0.01164718],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9434213,"threshold_uncertainty_score":0.9998443,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2485857082702152,"score_gpt":0.4431821905221668,"score_spread":0.1945964822519516,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}