{"id":"W797393888","doi":"10.1007/s12013-015-0528-5","title":"Bioengineered Colorectal Cancer Drugs: Orally Delivered Anti-Inflammatory Agents","year":2015,"lang":"en","type":"review","venue":"Cell Biochemistry and Biophysics","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"Inflammation; Immune system; Medicine; Colorectal cancer; Cancer; Inflammatory bowel disease; Gut flora; Gastrointestinal tract; Disease; Immunology; Pharmacology; Cancer research; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001433002,0.0007275192,0.001045716,0.00004545634,0.0001271421,0.00006282514,0.0004154964,0.0009627106,0.00001998821],"category_scores_gemma":[0.00001062666,0.0006580714,0.0003623487,0.0001908382,0.0001981134,0.000005296199,0.0003071614,0.0003563628,0.00003577135],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009448311,"about_ca_system_score_gemma":0.001030281,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001582096,"about_ca_topic_score_gemma":0.000001385637,"domain_scores_codex":[0.9978364,0.00006122942,0.0005021348,0.0008927516,0.0001758117,0.0005317393],"domain_scores_gemma":[0.9986107,0.00001043802,0.0003624619,0.0004897566,0.0001718205,0.0003548742],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005967799,0.0002892335,0.00002315798,0.0356546,0.0004899015,0.0000326308,0.0001023759,0.00000293717,0.735751,0.000004746661,0.02403263,0.2035571],"study_design_scores_gemma":[0.0005322867,0.0001061221,0.000004886691,0.001285769,0.000444646,0.00002503331,0.00004742669,0.000005344723,0.1104323,0.000003731313,0.8861898,0.0009226497],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.07369848,0.9243204,0.000003999427,0.000009947391,0.0003091714,0.0004542393,0.000808636,0.00003374695,0.0003614133],"genre_scores_gemma":[0.006264629,0.9885035,0.00009357603,0.00006404108,0.0008893536,0.00006419652,0.002963841,0.00009220063,0.001064704],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8621572,"threshold_uncertainty_score":0.9995871,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01612020345537575,"score_gpt":0.2855213887465021,"score_spread":0.2694011852911264,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}