{"id":"W797478951","doi":"","title":"Postnatal nonsense suppression therapy rescues Pax6-deficient congenital eye defects","year":2014,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"Ocular Disorders and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Nonsense; PAX6; Medicine; Ophthalmology; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004411926,0.0002709858,0.000200566,0.00009511361,0.0004477343,0.00005918327,0.0003558706,0.0001598719,0.00003381319],"category_scores_gemma":[0.0003876271,0.0002174046,0.00009672861,0.0003210351,0.002679601,0.00002083551,0.0002705684,0.0001231238,0.00005458633],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002695846,"about_ca_system_score_gemma":0.0002036345,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006491698,"about_ca_topic_score_gemma":0.000004264487,"domain_scores_codex":[0.9978721,0.0002545004,0.0002020292,0.0008106622,0.000325547,0.0005351939],"domain_scores_gemma":[0.9990208,0.0000371215,0.0001138147,0.0003796898,0.0001854905,0.0002630514],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007447522,0.0001880131,0.07134401,0.000002607859,0.00002824256,0.00005333517,0.0001340686,0.00001502574,0.9277514,0.00005493957,0.00006612657,0.0002877677],"study_design_scores_gemma":[0.0007729768,0.001801974,0.1181733,0.00001134987,0.00001071883,0.000132329,0.00009811076,0.0001147388,0.8776678,0.0004972978,0.0004636295,0.0002557848],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969769,0.0004965254,0.00001000732,0.0001217634,0.0002765506,0.0002735472,0.00001649595,0.0000197324,0.001808551],"genre_scores_gemma":[0.9988676,0.00002426933,0.0004202899,0.0003103005,0.00006874241,0.00002942064,0.00006146333,0.00002124934,0.0001966483],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05008363,"threshold_uncertainty_score":0.9873101,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01870097401175649,"score_gpt":0.3146227690066456,"score_spread":0.2959217949948891,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}