{"id":"W80618799","doi":"10.1097/01.fjc.0000205984.13395.9e","title":"Nicotine Effect on Cardiovascular System and Ion Channels","year":2006,"lang":"en","type":"review","venue":"Journal of Cardiovascular Pharmacology","topic":"Nicotinic Acetylcholine Receptors Study","field":"Biochemistry, Genetics and Molecular Biology","cited_by":103,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Nicotine; Nitric oxide; Superoxide; Vasodilation; Medicine; Free radical scavenger; Antioxidant; Internal medicine; Pharmacology; Cardiology; Endothelium; Endocrinology; Chemistry; Oxidative stress; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.004335599,0.0009548567,0.005481434,0.0004303664,0.0001281537,0.00004334589,0.0006744061,0.0009491266,0.000008120436],"category_scores_gemma":[0.0001203874,0.0007366354,0.009154475,0.0002890863,0.0001492548,0.000009666323,0.0003423998,0.001082235,0.00002572068],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002239107,"about_ca_system_score_gemma":0.0003179987,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001051398,"about_ca_topic_score_gemma":2.585878e-7,"domain_scores_codex":[0.993184,0.002991634,0.001461259,0.000873103,0.0008743266,0.0006156872],"domain_scores_gemma":[0.9973196,0.0001508655,0.001000465,0.0009281441,0.0003232287,0.0002776719],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002120423,0.0002195512,0.00000670902,0.01713211,0.08608218,0.0001632239,0.0000110199,0.002738497,0.0004497912,0.00000808768,0.01806405,0.8749127],"study_design_scores_gemma":[0.002830979,0.00165603,5.800783e-7,0.001731897,0.02324233,0.004249499,0.00000543011,0.000004823429,0.003818794,3.881585e-7,0.9618961,0.0005631535],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001570084,0.9903325,0.0005269649,0.000007995064,0.005785315,0.00131868,0.00002639533,0.00002241616,0.000409618],"genre_scores_gemma":[0.002196166,0.9864476,0.00007619013,0.00002924087,0.01079305,0.0000873738,0.00007121154,0.0001829538,0.0001162167],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.943832,"threshold_uncertainty_score":0.9995084,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01486810375878314,"score_gpt":0.3016225102254739,"score_spread":0.2867544064666907,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}