{"id":"W828489513","doi":"","title":"Rip3 knockdown rescues photoreceptor cell death in pde6c zebrafish model of achromatopsia","year":2013,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Zebrafish; Achromatopsia; Gene knockdown; Photoreceptor cell; Cell biology; Ophthalmology; Biology; Medicine; Neuroscience; Retina; Genetics; Cell culture; Retinal; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002705196,0.0007514514,0.0005267564,0.00109788,0.0004777493,0.000415537,0.0005733925,0.0009986926,0.004808778],"category_scores_gemma":[0.0002226147,0.0004364471,0.0008202372,0.0002602829,0.0009241545,0.0004356924,0.0004842874,0.001570251,0.001125375],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000690916,"about_ca_system_score_gemma":0.0005153359,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003444391,"about_ca_topic_score_gemma":0.005958298,"domain_scores_codex":[0.999653,0.00003233392,0.00004911891,0.00008579628,0.0001120818,0.00006769849],"domain_scores_gemma":[0.9997099,0.00003285673,0.00010769,0.00003088509,0.00002601237,0.0000926387],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001098013,0.00002526111,0.00009875018,0.00004100057,0.00000859835,0.000573108,0.00002134146,0.00006498281,0.9982985,0.0002100341,0.0001129785,0.0004357978],"study_design_scores_gemma":[0.0001406182,0.0002526259,0.009346103,0.00003295207,0.00009113937,0.002803237,0.0001430966,0.002242035,0.981666,0.0002497477,0.003004733,0.00002769489],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.985733,0.001118799,0.005641412,0.0006543311,0.0001509668,0.0001011981,0.001805167,0.0005787217,0.004216335],"genre_scores_gemma":[0.9777259,0.0009042705,0.004117051,0.000201919,0.00002262631,0.0001119775,0.0008448726,0.0002001422,0.01587121],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004808778,"threshold_uncertainty_score":0.016087,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02372060106804001,"score_gpt":0.2911423887122139,"score_spread":0.2674217876441739,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}