{"id":"W831960002","doi":"10.1139/o09-040","title":"Getting to the center of X-chromosome inactivation: the role of transgenesThis paper is one of a selection of papers published in this Special Issue, entitled 30th Annual International Asilomar Chromatin and Chromosomes Conference, and has undergone the Journal’s usual peer review process.","year":2009,"lang":"en","type":"review","venue":"Biochemistry and Cell Biology","topic":"Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"XIST; X-inactivation; Biology; Chromatin; Heterochromatin; X chromosome; Dosage compensation; Genetics; RNA; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004022691,0.0007554952,0.0008073751,0.001549521,0.000270249,0.0009542856,0.0007456075,0.001047726,0.003812845],"category_scores_gemma":[0.0004436612,0.0002242799,0.000209523,0.001662452,0.000477097,0.001508355,0.0004604376,0.001377918,0.00490908],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005733769,"about_ca_system_score_gemma":0.0006049647,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005807577,"about_ca_topic_score_gemma":0.0009598699,"domain_scores_codex":[0.9998816,0.00001591164,0.00001385311,0.00002901513,0.00005039091,0.000009205469],"domain_scores_gemma":[0.9998287,0.00005310373,0.00002629114,0.000008697632,0.00005679617,0.00002633713],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004397508,0.00004971708,0.0001331437,0.005716156,0.00002414289,0.0002406782,0.00004942879,0.0001849563,0.005947609,0.004702112,0.03127816,0.9516299],"study_design_scores_gemma":[0.000006107277,0.00003155003,0.0004024817,0.0006399396,0.00001768653,0.0009863121,0.00003503726,0.00004039631,0.001229061,0.0008047764,0.9957972,0.000009452048],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002504495,0.9939248,0.0006247498,0.0004374271,0.0008954292,0.000009256946,0.00002926129,0.00002477717,0.003803867],"genre_scores_gemma":[0.0008742182,0.993745,0.0008311764,0.0003002421,0.0002521244,0.00001220519,0.00005554334,0.000005942345,0.003923464],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003812845,"threshold_uncertainty_score":0.01275527,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01636492389916028,"score_gpt":0.2802786146101817,"score_spread":0.2639136907110214,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}