{"id":"W845428742","doi":"10.1139/y09-052","title":"IGF-1 receptor transactivation mediates Src-dependent cortactin phosphorylation in response to angiotensin IIThis article is one of a selection of papers published in a special issue celebrating the 125th anniversary of the Faculty of Medicine at the University of Manitoba.","year":2009,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Boniface Hospital","funders":"Infrastructure Canada; Canadian Institutes of Health Research; Hospital Research Foundation","keywords":"Cortactin; Proto-oncogene tyrosine-protein kinase Src; Cell biology; Biology; Transactivation; MAP kinase kinase kinase; Tyrosine kinase; Phosphorylation; Cancer research; Chemistry; Signal transduction; Protein kinase A; Biochemistry; Cytoskeleton; Cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000395323,0.00005808834,0.0001960762,0.00007778435,0.0000466759,5.572504e-7,0.0001155457,0.00008867421,0.0007613164],"category_scores_gemma":[0.00005738573,0.00003911797,0.0000538337,0.0001948308,0.0002588861,0.000009588434,0.000009856353,0.00009354645,6.3632e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004855452,"about_ca_system_score_gemma":0.000249024,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002000103,"about_ca_topic_score_gemma":0.01246647,"domain_scores_codex":[0.999229,0.0002667471,0.0002624376,0.00008572543,0.00006361817,0.00009243903],"domain_scores_gemma":[0.999298,0.00006710336,0.000365778,0.00005939937,0.0001691501,0.00004056116],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002270618,0.00003076361,0.00949239,0.00001104806,0.00005737343,6.469477e-7,0.002301975,0.0005383739,0.9818665,0.000003307453,0.002589443,0.0008375678],"study_design_scores_gemma":[0.000738756,0.0004807229,0.2548338,0.00002211797,0.00003683769,0.000002530949,0.0009933653,0.00003119106,0.7421558,0.00001882313,0.0006586506,0.00002734608],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996165,0.0002350102,0.00000643982,0.003296645,0.0001153508,0.0001188875,0.00003071229,2.063557e-7,0.00003173544],"genre_scores_gemma":[0.9994984,0.0000998828,0.00002291262,0.0002295306,0.000119055,2.669168e-7,0.000003833339,0.000002378651,0.00002373317],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2453414,"threshold_uncertainty_score":0.8335881,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009776929237396136,"score_gpt":0.2361995400811731,"score_spread":0.2264226108437769,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}