{"id":"W84591217","doi":"10.1182/blood.v122.21.2.2","title":"Initial Phase 3 Results Of The First (Frontline Investigation Of Lenalidomide + Dexamethasone Versus Standard Thalidomide) Trial (MM-020/IFM 07 01) In Newly Diagnosed Multiple Myeloma (NDMM) Patients (Pts) Ineligible For Stem Cell Transplantation (SCT)","year":2013,"lang":"en","type":"article","venue":"Blood","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen Elizabeth II Health Sciences Centre; Princess Margaret Cancer Centre; University of Calgary; University of Alberta","funders":"","keywords":"Lenalidomide; Medicine; Multiple myeloma; Thalidomide; Internal medicine; Melphalan; Clinical endpoint; Adverse effect; Surgery; Dexamethasone; Phases of clinical research; Oncology; Gastroenterology; Randomized controlled trial; Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005178371,0.0002884059,0.0006846146,0.0002437193,0.00009653287,0.00003032605,0.0002052393,0.0001753016,0.00003650638],"category_scores_gemma":[0.00089879,0.0002116799,0.0002276384,0.0003714579,0.0001586065,0.0002859196,0.00004144613,0.0001998736,0.000009660803],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001298974,"about_ca_system_score_gemma":0.0003270338,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001858067,"about_ca_topic_score_gemma":0.00141966,"domain_scores_codex":[0.9970567,0.0002318874,0.001118065,0.0004157595,0.0007473865,0.0004302509],"domain_scores_gemma":[0.9968377,0.001549935,0.000520463,0.0004459869,0.0004326795,0.000213252],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8294232,0.007699247,0.1253804,0.001393504,0.0005562715,0.00005399925,0.003553521,0.0001223509,0.01875228,0.0000132719,0.0008708804,0.01218101],"study_design_scores_gemma":[0.5895419,0.005327838,0.03770725,0.0003067064,0.0003188695,0.000001523791,0.0001614187,0.0003782143,0.3659968,0.00003146922,0.00008189421,0.0001461757],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918755,0.0001012146,0.0001365304,0.0002388265,0.0002568802,0.005795672,0.00143256,0.00002542015,0.0001374486],"genre_scores_gemma":[0.9967542,0.00009051603,0.001516623,0.00003579596,0.0001530421,0.0005542404,0.0007962715,0.00004141755,0.00005786582],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3472445,"threshold_uncertainty_score":0.8632054,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04326538170802355,"score_gpt":0.3089572128148892,"score_spread":0.2656918311068657,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}