{"id":"W84591217","doi":"10.1182/blood.v122.21.2.2","title":"Initial Phase 3 Results Of The First (Frontline Investigation Of Lenalidomide + Dexamethasone Versus Standard Thalidomide) Trial (MM-020/IFM 07 01) In Newly Diagnosed Multiple Myeloma (NDMM) Patients (Pts) Ineligible For Stem Cell Transplantation (SCT)","year":2013,"lang":"en","type":"article","venue":"Blood","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen Elizabeth II Health Sciences Centre; Princess Margaret Cancer Centre; University of Calgary; University of Alberta","funders":"","keywords":"Lenalidomide; Medicine; Multiple myeloma; Thalidomide; Internal medicine; Melphalan; Clinical endpoint; Adverse effect; Surgery; Dexamethasone; Phases of clinical research; Oncology; Gastroenterology; Randomized controlled trial; Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002646719,0.001199884,0.002059392,0.0003676511,0.0004569789,0.001367911,0.001049896,0.00128973,0.007365589],"category_scores_gemma":[0.001726628,0.0004316369,0.001652415,0.0003788229,0.0006772481,0.0008821792,0.0004320942,0.003737612,0.0009300621],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001349155,"about_ca_system_score_gemma":0.001188693,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009277146,"about_ca_topic_score_gemma":0.003883016,"domain_scores_codex":[0.9993407,0.0004042492,0.00002522145,0.00007989183,0.0000449771,0.0001047944],"domain_scores_gemma":[0.9985101,0.0003196438,0.0003193005,0.00007564952,0.0000940986,0.0006812718],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9282377,0.01672001,0.002554787,0.0007493723,0.001202172,0.0001139763,0.0001144359,0.0009976991,0.006315091,0.0001843797,0.006759415,0.03605103],"study_design_scores_gemma":[0.8428742,0.1449933,0.006261558,0.0001005756,0.0009553515,0.0001469501,0.00003897876,0.000498986,0.001136687,0.0003804272,0.002589232,0.00002371575],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9651353,0.01165344,0.0007064047,0.002481152,0.0003691286,0.005189481,0.008517219,0.0001519063,0.005796052],"genre_scores_gemma":[0.972331,0.004146169,0.00259885,0.002988385,0.0004846826,0.005523554,0.007628987,0.00004676074,0.004251497],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007365589,"threshold_uncertainty_score":0.02464032,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04326538170802355,"score_gpt":0.3089572128148892,"score_spread":0.2656918311068657,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}