{"id":"W849129057","doi":"10.1139/y10-056","title":"Endothelin signaling via guanine exchange factor C3G in renal glomerular mesangial cellsThis article is one of a selection of papers published in the two-part special issue entitled 20 Years of Endothelin Research.","year":2010,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Renal Diseases and Glomerulopathies","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institutes of Health; American Heart Association","keywords":"Mesangial cell; Guanine nucleotide exchange factor; Internal medicine; Endocrinology; Rap1; Biology; Endothelin 1; Cell biology; Kidney; Signal transduction; Medicine; Receptor","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001096297,0.0002852902,0.0001660526,0.0002115868,0.0002366096,0.0002684675,0.0001572096,0.0004551029,0.0005220096],"category_scores_gemma":[0.00006443772,0.00008457756,0.0002082579,0.0002772004,0.0001817835,0.0002325724,0.0002238191,0.0004408273,0.0001879961],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003741141,"about_ca_system_score_gemma":0.0002940763,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001261005,"about_ca_topic_score_gemma":0.001472851,"domain_scores_codex":[0.9999186,0.00001180865,0.000006063594,0.00001650052,0.00002337027,0.00002366116],"domain_scores_gemma":[0.9999392,0.000008551174,0.00001226401,0.000007874818,0.00001141533,0.00002060942],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007658191,0.000007692238,0.0002501678,0.00003955083,0.000002834199,0.00008976176,0.00001940285,0.0000247061,0.998149,0.0001538273,0.00005464686,0.001131774],"study_design_scores_gemma":[0.00002914835,0.0001468322,0.02514057,0.00001822158,0.00003202459,0.0007024488,0.00007780286,0.001245459,0.9646108,0.0003360308,0.007646976,0.00001390323],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9844499,0.009612617,0.003039479,0.0004068534,0.00008322232,0.00002299103,0.0004794792,0.00009918227,0.001806336],"genre_scores_gemma":[0.9906507,0.004778094,0.001937552,0.0001595684,0.00002727788,0.00002631795,0.0003951239,0.00001213304,0.002013133],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001261005,"threshold_uncertainty_score":0.002714336,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02071387623558316,"score_gpt":0.3021045727797992,"score_spread":0.281390696544216,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}