{"id":"W856477841","doi":"10.3727/096368915x688506","title":"Porcine Islet-Specific Tolerance Induced by the Combination of Anti-LFA-1 and Anti-CD154 mAbs is Dependent on PD-1","year":2016,"lang":"en","type":"article","venue":"Cell Transplantation","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Islet; Spleen; CD154; Monoclonal antibody; Immune tolerance; Medicine; Immunology; Xenotransplantation; Transplantation; Kidney; Cancer research; Antibody; Biology; Endocrinology; Internal medicine; Antigen; CD40; Diabetes mellitus; Cytotoxic T cell; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001821282,0.0004014502,0.0003689342,0.0002198008,0.000129854,0.0002760426,0.0001819296,0.0002598505,0.0009370691],"category_scores_gemma":[0.00008442961,0.0001269416,0.0003530776,0.0001084839,0.0001803201,0.0001906411,0.0001542536,0.001015055,0.0001910363],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001201678,"about_ca_system_score_gemma":0.0001205835,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001028986,"about_ca_topic_score_gemma":0.0001707122,"domain_scores_codex":[0.9998063,0.00003339096,0.00002063925,0.0000425882,0.00004007917,0.00005708329],"domain_scores_gemma":[0.9998714,0.00001490042,0.00004237001,0.00001610434,0.000008185383,0.0000470774],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002376961,0.0001061614,0.0002534213,0.00002118124,0.000005682381,0.00004868306,0.000008285505,0.00004214887,0.9982613,0.00003332009,0.00002163151,0.0009605976],"study_design_scores_gemma":[0.0001047932,0.005908821,0.008816284,0.00001753236,0.00006360489,0.0009356034,0.00003302807,0.001223061,0.980643,0.00005943012,0.002184633,0.00001028609],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973378,0.0006635156,0.0009590529,0.00004126855,0.00003224962,0.00001870144,0.00007308544,0.00002793718,0.0008464513],"genre_scores_gemma":[0.9973366,0.000452653,0.0008134888,0.0000813753,0.00002306377,0.00003916539,0.0001775206,0.00001187472,0.001064284],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009370691,"threshold_uncertainty_score":0.003134847,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01706438258869468,"score_gpt":0.2317172841539626,"score_spread":0.214652901565268,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}