{"id":"W858977218","doi":"","title":"LXR Activation May Correct Glucose Mediated Dysfunction In Vitro and Modulate Diabetic Retinopathy (DR) In Type 1 Diabetes Model","year":2012,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"Advanced Glycation End Products research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Diabetic retinopathy; Medicine; Type 2 diabetes; Diabetes mellitus; In vitro; Retinopathy; Internal medicine; Endocrinology; Ophthalmology; Chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003097768,0.0004223909,0.0003923029,0.0002812779,0.0002392843,0.0005103063,0.0002140561,0.0003962245,0.003090523],"category_scores_gemma":[0.0001828958,0.0001680708,0.0004498893,0.0002107265,0.0002509335,0.0003068647,0.0001886805,0.001525247,0.0005339126],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000228302,"about_ca_system_score_gemma":0.0002841566,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003429747,"about_ca_topic_score_gemma":0.0004144271,"domain_scores_codex":[0.9997876,0.00005947205,0.00002664837,0.00003545212,0.00002916501,0.000061597],"domain_scores_gemma":[0.9998897,0.00001816508,0.00002849908,0.00002436335,0.00001280034,0.00002649492],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002660508,0.0005723479,0.000268115,0.0001274697,0.00002263988,0.0001234628,0.00004224797,0.0001020373,0.9908814,0.000439153,0.000286896,0.004473746],"study_design_scores_gemma":[0.0001869798,0.00171582,0.001521308,0.0000155024,0.00006295615,0.0001763007,0.00006818924,0.0004709536,0.9925869,0.0001842293,0.003002322,0.000008491254],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9896231,0.002775589,0.003655987,0.0006608705,0.0002908053,0.00005925584,0.0004739633,0.0002268179,0.00223351],"genre_scores_gemma":[0.9875166,0.002293842,0.002766461,0.0002298364,0.00005369648,0.00008172633,0.0008493296,0.00004181874,0.006166689],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003090523,"threshold_uncertainty_score":0.01033884,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03395476007350963,"score_gpt":0.3318986142800454,"score_spread":0.2979438542065357,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}