{"id":"W86086534","doi":"10.1089/mab.2013.0058","title":"Development of Monoclonal Antibodies to Interrogate Functional Domains and Isoforms of FREM1 Protein","year":2014,"lang":"en","type":"article","venue":"Monoclonal Antibodies in Immunodiagnosis and Immunotherapy","topic":"Ocular Disorders and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Public Health Agency of Canada","funders":"Public Health Agency of Canada","keywords":"Monoclonal antibody; Gene isoform; Biology; Antibody; Computational biology; Focus (optics); Virology; Immunology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000254639,0.000263826,0.000390274,0.0001439456,0.0001265513,0.00002256642,0.0001402619,0.0001086375,0.00001959904],"category_scores_gemma":[0.00002534221,0.0002231004,0.00009322946,0.00009555658,0.0002261059,0.00001616209,0.0001738803,0.00007384019,0.000001693239],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001464139,"about_ca_system_score_gemma":0.00004141192,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001306894,"about_ca_topic_score_gemma":0.0001119936,"domain_scores_codex":[0.9986739,0.00004814116,0.0005072509,0.0003540548,0.0001604266,0.0002562036],"domain_scores_gemma":[0.99945,0.0000259317,0.0001608425,0.0002384728,0.00007986924,0.00004489657],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0006500724,0.000447299,0.1648638,0.00007387602,0.0003986398,0.000001009205,0.0008917009,0.00001739351,0.7927741,0.000360308,0.00005876985,0.03946305],"study_design_scores_gemma":[0.002225047,0.0006868315,0.522072,0.0002067846,0.00001351958,0.000005533843,0.0003500946,0.00003446669,0.4668824,0.0003193867,0.006885225,0.0003187782],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924453,0.006307815,0.0005376773,0.0001322836,0.00007246508,0.0003280641,0.00002612649,0.000005649571,0.0001446554],"genre_scores_gemma":[0.9855277,0.002977182,0.01114139,0.0001034053,0.00002164361,0.00006972512,0.00005880972,0.00002468009,0.00007549152],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3572082,"threshold_uncertainty_score":0.909777,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008737797045428783,"score_gpt":0.238811790981572,"score_spread":0.2300739939361432,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}