{"id":"W86086534","doi":"10.1089/mab.2013.0058","title":"Development of Monoclonal Antibodies to Interrogate Functional Domains and Isoforms of FREM1 Protein","year":2014,"lang":"en","type":"article","venue":"Monoclonal Antibodies in Immunodiagnosis and Immunotherapy","topic":"Ocular Disorders and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Public Health Agency of Canada","funders":"Public Health Agency of Canada","keywords":"Monoclonal antibody; Gene isoform; Biology; Antibody; Computational biology; Focus (optics); Virology; Immunology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009682457,0.001538805,0.0006097311,0.001222744,0.0003697123,0.0004530969,0.0009058495,0.001282447,0.002038727],"category_scores_gemma":[0.0008258538,0.0006831556,0.0005519618,0.0005503275,0.0002761637,0.0004362595,0.0005744726,0.001577791,0.0009860538],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008162705,"about_ca_system_score_gemma":0.0002625976,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007428423,"about_ca_topic_score_gemma":0.001167132,"domain_scores_codex":[0.9990302,0.0001797457,0.00008394155,0.0002569148,0.0001766026,0.0002726004],"domain_scores_gemma":[0.9994166,0.0001830739,0.00008755406,0.00006506068,0.00017359,0.00007416401],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008694918,0.0000930357,0.0004028319,0.00007731799,0.00002304223,0.00006029276,0.00002238758,0.0001413967,0.9941053,0.0001578885,0.0002133477,0.004616205],"study_design_scores_gemma":[0.0001711193,0.001011624,0.00875838,0.00007272743,0.0001487866,0.001589112,0.00006508746,0.006007978,0.96068,0.0003071444,0.02116071,0.00002733627],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8866352,0.01130214,0.08979449,0.000745411,0.0002587382,0.001073452,0.001249492,0.0007756405,0.008165378],"genre_scores_gemma":[0.8875434,0.006958213,0.09149747,0.00112588,0.0001701268,0.002119255,0.004715447,0.0001782805,0.005692],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002038727,"threshold_uncertainty_score":0.006820202,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008737797045428783,"score_gpt":0.238811790981572,"score_spread":0.2300739939361432,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}