{"id":"W88467877","doi":"10.1161/circ.124.suppl_21.a17075","title":"Abstract 17075: Preferential Targeting of Bnip3 Isoforms to Mitochondria or Endoplasmic Reticulum During Metabolic Stress Promotes Autophagy or Cell Survival of Post-Natal Ventricular Myocytes","year":2011,"lang":"en","type":"article","venue":"Circulation","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Boniface Hospital","funders":"","keywords":"Endoplasmic reticulum; Autophagy; Medicine; Cell biology; Mitochondrion; Myocyte; Gene isoform; Cell; Unfolded protein response; Internal medicine; Apoptosis; Biochemistry; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001110932,0.0003653585,0.0002534254,0.0001545693,0.0001954528,0.0002260308,0.0002463925,0.0002761708,0.002165889],"category_scores_gemma":[0.00008316666,0.0001177065,0.0001994079,0.0001537716,0.0002675269,0.0002042995,0.0002257473,0.0005186628,0.0007680301],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003464464,"about_ca_system_score_gemma":0.0002777785,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005195541,"about_ca_topic_score_gemma":0.0006639254,"domain_scores_codex":[0.9998972,0.00001124765,0.0000122763,0.00002445936,0.00002319662,0.00003149945],"domain_scores_gemma":[0.9999324,0.00001068716,0.00001597454,0.000006851521,0.000006834345,0.00002725213],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009593222,0.000009802749,0.00005773391,0.00002085658,0.000001964133,0.00005530232,0.000005526275,0.000008107364,0.9994,0.0000383443,0.00003001132,0.000276441],"study_design_scores_gemma":[0.00003586668,0.0002942199,0.007182512,0.000009638373,0.00001734343,0.0004280458,0.00003421815,0.000297614,0.9888991,0.00005190409,0.002744072,0.000005633955],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938022,0.001178014,0.001499063,0.0001670363,0.00007200619,0.00003583386,0.0009057067,0.00006338848,0.002276808],"genre_scores_gemma":[0.9862176,0.001124423,0.002802489,0.0002160291,0.00004627918,0.0001043323,0.002602733,0.00005983856,0.006826304],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002165889,"threshold_uncertainty_score":0.0072456,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01868598769948618,"score_gpt":0.2328610546982645,"score_spread":0.2141750669987784,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}