{"id":"W895230571","doi":"10.1016/j.ijpharm.2015.07.021","title":"Lipid-based nanoparticles containing cationic derivatives of PTA (1,3,5-triaza-7-phosphaadamantane) as innovative vehicle for Pt complexes: Production, characterization and in vitro studies","year":2015,"lang":"en","type":"article","venue":"International Journal of Pharmaceutics","topic":"Synthesis and Characterization of Heterocyclic Compounds","field":"Chemistry","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Petroleum Technology Alliance Canada","keywords":"Phosphine; Cationic polymerization; Chemistry; Nanoparticle; Dithiocarbamate; Ligand (biochemistry); Platinum; Alkylation; Combinatorial chemistry; Yield (engineering); Metal; In vitro; Stereochemistry; Nuclear chemistry; Organic chemistry; Nanotechnology; Materials science; Biochemistry; Catalysis; Receptor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004450549,0.0001398468,0.0003093681,0.0001995102,0.00004503366,0.00004594054,0.0002135976,0.00004356518,0.00002360345],"category_scores_gemma":[0.0009301715,0.0001338092,0.00004912083,0.0001686006,0.0001193489,0.0003960113,0.00004592417,0.0001195208,6.105393e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001779103,"about_ca_system_score_gemma":0.0001967401,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003470613,"about_ca_topic_score_gemma":0.000003281417,"domain_scores_codex":[0.9984589,0.00004718928,0.0008214091,0.0001524105,0.0003903523,0.0001297708],"domain_scores_gemma":[0.9964042,0.0002772192,0.0009322921,0.0000801557,0.002238026,0.00006805362],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001826295,0.0002034635,0.01144258,0.0000627625,0.0002054556,0.000005539116,0.001715308,0.000199634,0.9762393,0.0001155952,0.00001266202,0.007971424],"study_design_scores_gemma":[0.002504676,0.00006605685,0.002047642,0.0002185738,0.00003447546,0.0000390877,0.001220343,0.002545922,0.9865336,0.0001999485,0.00446574,0.0001239092],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962501,0.0003956638,0.00091619,0.001709306,0.0005405089,0.0001072708,0.00004420851,0.00001059809,0.00002615346],"genre_scores_gemma":[0.9984399,0.0002723632,0.0006165029,0.0002052497,0.0003471637,0.000014465,0.00005108062,0.00001680346,0.00003645848],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01029434,"threshold_uncertainty_score":0.5456579,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0947520671199736,"score_gpt":0.3790171588661813,"score_spread":0.2842650917462077,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}