{"id":"W907204266","doi":"10.1007/7651_2015_269","title":"Quantitative Analysis of Intra-chromosomal Contacts: The 3C-qPCR Method","year":2015,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Institute of Cancer Research; Institut National Du Cancer; Centre National de la Recherche Scientifique; Ligue Contre le Cancer","keywords":"Normalization (sociology); Chromosome conformation capture; Chromatin; Chromosome; Computational biology; Biology; Population; Genetics; DNA; Gene; Gene expression; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008357766,0.006268224,0.006589394,0.006458632,0.004468452,0.004423407,0.006822446,0.005258487,0.01665511],"category_scores_gemma":[0.006742511,0.005240581,0.005789741,0.006979162,0.006696263,0.002594033,0.004395357,0.01904314,0.01449074],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003893726,"about_ca_system_score_gemma":0.004576114,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006252093,"about_ca_topic_score_gemma":0.01482376,"domain_scores_codex":[0.9792286,0.004479875,0.001317077,0.0066315,0.00644124,0.001901729],"domain_scores_gemma":[0.9912061,0.003491235,0.0006208324,0.00224666,0.001976008,0.0004591245],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002505703,0.000201322,0.0003123443,0.0008898025,0.0001052976,0.00006725395,0.0003141348,0.0008531674,0.9774053,0.004152815,0.00234323,0.01310469],"study_design_scores_gemma":[0.0001041865,0.000174488,0.001660807,0.0001223624,0.0001509416,0.0001315059,0.00006520639,0.01237962,0.9625401,0.001871847,0.0206271,0.0001719394],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.01080247,0.0009660017,0.9693439,0.0003129865,0.0007314147,0.001467263,0.005975933,0.005125015,0.00527505],"genre_scores_gemma":[0.03297482,0.00176614,0.9265832,0.0007514752,0.0001756475,0.009738724,0.007617367,0.005683286,0.0147094],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.01665511,"threshold_uncertainty_score":0.05571693,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0286176330784913,"score_gpt":0.401524161847526,"score_spread":0.3729065287690347,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}