{"id":"W918917685","doi":"10.1096/fasebj.27.1_supplement.386.8","title":"Phenylephrine‐induced cardiomyocyte hypertrophy and calcification are regulated by CD73‐TNAP interaction and inhibited by adenosine receptor activation","year":2013,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Medical Imaging and Pathology Studies","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Downregulation and upregulation; Phenylephrine; Internal medicine; Endocrinology; Muscle hypertrophy; Myocyte; Calcification; Chemistry; Adenosine; Intracellular; Pyrophosphate; Cardiac myocyte; Medicine; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002599507,0.0001373262,0.0002370247,0.00007385221,0.0002841042,0.00005778268,0.00004163183,0.00008346063,0.00006927187],"category_scores_gemma":[0.0002422477,0.00008586889,0.00003371053,0.0001244876,0.0001545362,0.0001849109,0.00002761976,0.0004906182,0.0000143829],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005168699,"about_ca_system_score_gemma":0.00001544497,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007445832,"about_ca_topic_score_gemma":4.308402e-7,"domain_scores_codex":[0.9990663,0.0001525337,0.0002448647,0.0001693285,0.0001968283,0.0001701368],"domain_scores_gemma":[0.9992312,0.0001001555,0.0001997189,0.0001333501,0.0001776867,0.0001578909],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000117546,0.00003583983,0.004124019,0.00001531543,0.00009481422,0.000002671832,0.0004043826,2.878951e-7,0.9168862,0.000001415815,0.06358463,0.01473292],"study_design_scores_gemma":[0.006151594,0.0007446445,0.1368295,0.0008359273,0.0005104062,0.002413945,0.005099622,0.001280582,0.8286108,0.0001315497,0.01691891,0.0004725271],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.979055,0.0009874007,0.0003623213,0.01900703,0.000172324,0.0002253797,0.000005592246,0.00003383591,0.0001510562],"genre_scores_gemma":[0.9974503,0.000568338,0.0001395014,0.0008765085,0.0002595286,0.00001426482,0.00004633917,0.00001486903,0.0006303638],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1327055,"threshold_uncertainty_score":0.3501632,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02095462487020927,"score_gpt":0.2579932942756761,"score_spread":0.2370386694054668,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}