{"id":"W91996105","doi":"","title":"RNA-cleaving properties of human apurinic/apyrimidinic endonuclease 1 (APE1).","year":2010,"lang":"en","type":"article","venue":"PubMed","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Northern British Columbia","funders":"","keywords":"Endoribonuclease; AP site; Endonuclease; RNA; Messenger RNA; Molecular biology; Cleave; DNA-(apurinic or apyrimidinic site) lyase; Biology; Cell biology; Chemistry; Biochemistry; Enzyme; Gene; RNase P","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008570489,0.0007993497,0.0003961174,0.0003189286,0.000204274,0.0004645401,0.0003583389,0.0006186255,0.00171777],"category_scores_gemma":[0.0009243213,0.0002374783,0.0006703156,0.0001867345,0.000263296,0.0004097805,0.0002661143,0.0009459736,0.001105129],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002784499,"about_ca_system_score_gemma":0.0001897999,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002297298,"about_ca_topic_score_gemma":0.0002392665,"domain_scores_codex":[0.9995044,0.0001221906,0.00004868427,0.0001470868,0.0001220916,0.00005545207],"domain_scores_gemma":[0.9992906,0.0002446004,0.000153353,0.00008716647,0.0001390949,0.0000851631],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007062069,0.00002163828,0.0005717764,0.0002062547,0.0000236198,0.00006743881,0.00002105197,0.0001237922,0.9926913,0.00007707169,0.00006224342,0.00606308],"study_design_scores_gemma":[0.000005152897,0.0001593144,0.002722242,0.000006479338,0.00001776473,0.0006991112,0.000008216915,0.0003619985,0.9926512,0.00005190576,0.003309496,0.000007169197],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8553273,0.0629213,0.07079744,0.0007151574,0.0002707764,0.0002458,0.001569603,0.0003026848,0.007849848],"genre_scores_gemma":[0.9519593,0.007825582,0.02838099,0.0002588843,0.00006944493,0.0001155232,0.003519885,0.00006342236,0.007806931],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00171777,"threshold_uncertainty_score":0.005746543,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02743637199037417,"score_gpt":0.2288343705506918,"score_spread":0.2013979985603176,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}