{"id":"W923874788","doi":"10.1016/j.jmb.2015.07.006","title":"Structural and Functional Characterization of a Novel Family GH115 4-O-Methyl-α-Glucuronidase with Specificity for Decorated Arabinogalactans","year":2015,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Polysaccharides and Plant Cell Walls","field":"Agricultural and Biological Sciences","cited_by":27,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada; Diamond Light Source; European Molecular Biology Organization","keywords":"Arabinogalactan; Bacteroides thetaiotaomicron; Glycoside hydrolase; Biochemistry; Biology; Periplasmic space; Galactan; Glucuronic acid; Cell wall; Polysaccharide; Enzyme; Bacteria; Bacteroides; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001328973,0.0003711057,0.0002527869,0.0001869564,0.0001216076,0.0002518165,0.0002841672,0.0002016372,0.0005427635],"category_scores_gemma":[0.0001648278,0.0000953989,0.0004365483,0.0002447286,0.0002047619,0.0001737914,0.000198011,0.0003258792,0.0002715015],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003465677,"about_ca_system_score_gemma":0.0002030933,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00175166,"about_ca_topic_score_gemma":0.001060079,"domain_scores_codex":[0.9999223,0.000009950245,0.000007179918,0.00001852664,0.00002288042,0.00001919426],"domain_scores_gemma":[0.9999009,0.00001204841,0.00002675627,0.00001238868,0.00001688083,0.00003102316],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008134275,0.00001485944,0.000385965,0.00001742326,0.000005437995,0.00005814813,0.00001065627,0.00004835793,0.9982838,0.00004155092,0.00001923632,0.001033173],"study_design_scores_gemma":[0.000009706414,0.0002090834,0.01394366,0.000005430409,0.00004090124,0.00061856,0.00007625765,0.001189856,0.9805096,0.00004680442,0.003341843,0.000008284477],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955734,0.0008487367,0.00275437,0.00005327364,0.00001698576,0.00001487138,0.0002782178,0.00002613063,0.0004340004],"genre_scores_gemma":[0.9916569,0.0004432889,0.004022782,0.00004011947,0.000006246524,0.00001237316,0.00212169,0.00001870072,0.001677996],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00175166,"threshold_uncertainty_score":0.003482938,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03758456634516957,"score_gpt":0.2323276499118509,"score_spread":0.1947430835666814,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}