{"id":"W923874788","doi":"10.1016/j.jmb.2015.07.006","title":"Structural and Functional Characterization of a Novel Family GH115 4-O-Methyl-α-Glucuronidase with Specificity for Decorated Arabinogalactans","year":2015,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Polysaccharides and Plant Cell Walls","field":"Agricultural and Biological Sciences","cited_by":27,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada; Diamond Light Source; European Molecular Biology Organization","keywords":"Arabinogalactan; Bacteroides thetaiotaomicron; Glycoside hydrolase; Biochemistry; Biology; Periplasmic space; Galactan; Glucuronic acid; Cell wall; Polysaccharide; Enzyme; Bacteria; Bacteroides; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002341371,0.00009819827,0.0002194791,0.00002366491,0.00003433377,0.00001550859,0.00008308869,0.00008621754,0.00001384797],"category_scores_gemma":[0.00004822776,0.00003676568,0.0000565517,0.000112042,0.00006033166,0.00006951166,0.00001665726,0.00008240592,2.817301e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001231761,"about_ca_system_score_gemma":0.00003447888,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002756429,"about_ca_topic_score_gemma":0.00001571601,"domain_scores_codex":[0.999341,0.00004608228,0.0002623263,0.000115944,0.0001005008,0.0001342011],"domain_scores_gemma":[0.9991327,0.00007276729,0.0003606482,0.00002491041,0.0003044592,0.0001045287],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000489149,0.00003401419,0.004196106,0.000003583475,0.00003396981,0.00000419491,0.00001713292,0.0000171114,0.992544,0.0003087533,0.00001505154,0.002336917],"study_design_scores_gemma":[0.003900589,0.007740852,0.4858457,0.00007547963,0.0001585118,0.0007272509,0.0003159811,0.001600091,0.4934647,0.001866087,0.003786903,0.0005178267],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953465,0.0001103238,0.003886679,0.0002621843,0.0001393297,0.0001021228,0.0001286575,0.000003779403,0.00002037338],"genre_scores_gemma":[0.9988148,0.00002380106,0.0008101627,0.0001228075,0.0001156185,0.000001153027,0.00009794207,0.000001003244,0.0000127123],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4990793,"threshold_uncertainty_score":0.1499261,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03758456634516957,"score_gpt":0.2323276499118509,"score_spread":0.1947430835666814,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}