{"id":"W92851269","doi":"10.1007/978-1-60761-421-0_6","title":"In Vivo Modulation of Gene Expression by Lentiviral Transduction in “Human Immune System” Rag2−/−γc −/− Mice","year":2006,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Wellcome Trust","keywords":"Immune system; Biology; Haematopoiesis; Progenitor cell; CD11c; Transduction (biophysics); Myeloid; Immunology; Ex vivo; Cell biology; Dendritic cell; Cancer research; Stem cell; In vivo; Phenotype; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006768874,0.0005937987,0.0002990233,0.0005842856,0.0002251792,0.0007279877,0.0004926297,0.0006380953,0.002417864],"category_scores_gemma":[0.0002194176,0.0002840428,0.0003587787,0.0002365649,0.0006183016,0.0003295728,0.0002610248,0.001108327,0.0008725022],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004070347,"about_ca_system_score_gemma":0.0003965491,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005848662,"about_ca_topic_score_gemma":0.0005697607,"domain_scores_codex":[0.9995066,0.00009383835,0.00007763642,0.0001436445,0.00009924093,0.00007901304],"domain_scores_gemma":[0.9997712,0.00003823312,0.00007375892,0.00004701956,0.00001782097,0.00005188554],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000170561,0.0001280535,0.00009321377,0.00003593797,0.000008166621,0.00004517822,0.00003759183,0.0001104151,0.9971249,0.0005320364,0.0001149582,0.001598949],"study_design_scores_gemma":[0.00008219689,0.0005409502,0.0005927492,0.0000107048,0.00002975654,0.0002721456,0.00001987629,0.0008989113,0.9910935,0.0001234485,0.006328278,0.000007478756],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9578822,0.002824235,0.02981639,0.0004502958,0.0003133632,0.0006370834,0.002574284,0.001125223,0.004376986],"genre_scores_gemma":[0.9595206,0.002704976,0.02341055,0.0003038916,0.00006884603,0.0006828301,0.002491381,0.0002645357,0.01055236],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002417864,"threshold_uncertainty_score":0.008088529,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01467227319334302,"score_gpt":0.3647305319363963,"score_spread":0.3500582587430533,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}