{"id":"W934854646","doi":"10.1038/srep12357","title":"IRGM1 enhances B16 melanoma cell metastasis through PI3K-Rac1 mediated epithelial mesenchymal transition","year":2015,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Neurological Institute and Hospital","funders":"","keywords":"RAC1; Melanoma; Epithelial–mesenchymal transition; Metastasis; Cell migration; Cancer research; Cell biology; Cell; Biology; Chemistry; Cancer; Signal transduction; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001108882,0.0003100986,0.0002323527,0.0003046868,0.0001565004,0.0002151707,0.0001382246,0.0002506839,0.001460496],"category_scores_gemma":[0.0000746658,0.0001119113,0.0002667458,0.0001539562,0.000208948,0.0002008674,0.0001796566,0.0008795652,0.0003517924],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002743566,"about_ca_system_score_gemma":0.0002449459,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008167708,"about_ca_topic_score_gemma":0.001535914,"domain_scores_codex":[0.9999037,0.00001645103,0.000007090401,0.00001302516,0.00002562663,0.00003413837],"domain_scores_gemma":[0.9999464,0.000005259032,0.00001318972,0.000005107549,0.000005734926,0.00002433867],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002182777,0.0001258516,0.0001961595,0.00007917772,0.00000546885,0.00003834094,0.00001896782,0.00008744338,0.9972873,0.00008184486,0.0001212242,0.001739996],"study_design_scores_gemma":[0.00006669118,0.001203533,0.008754031,0.00001520508,0.00002592185,0.000158228,0.00005727195,0.001484631,0.9841817,0.00007682171,0.003969735,0.000006339448],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951448,0.001789346,0.0006567835,0.000198373,0.00003156095,0.00002745926,0.0002086242,0.00010799,0.001835094],"genre_scores_gemma":[0.99494,0.001109374,0.001122948,0.00006811728,0.000008285928,0.00003745456,0.0003420623,0.00001428469,0.002357382],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001460496,"threshold_uncertainty_score":0.004885852,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03331286894283186,"score_gpt":0.2811114191246911,"score_spread":0.2477985501818592,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}