{"id":"W934854646","doi":"10.1038/srep12357","title":"IRGM1 enhances B16 melanoma cell metastasis through PI3K-Rac1 mediated epithelial mesenchymal transition","year":2015,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Neurological Institute and Hospital","funders":"","keywords":"RAC1; Melanoma; Epithelial–mesenchymal transition; Metastasis; Cell migration; Cancer research; Cell biology; Cell; Biology; Chemistry; Cancer; Signal transduction; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.002178642,0.0003033528,0.0006001933,0.0002185606,0.0002313665,0.0001701633,0.0001254315,0.0001293751,0.0009196915],"category_scores_gemma":[0.000212021,0.0002426983,0.000307253,0.0009027272,0.0003763886,0.0004125421,0.00004975254,0.000219682,0.000229362],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001505185,"about_ca_system_score_gemma":0.0007991901,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004030036,"about_ca_topic_score_gemma":0.0001156319,"domain_scores_codex":[0.9959918,0.0001127675,0.0008387264,0.001073324,0.001405593,0.0005777875],"domain_scores_gemma":[0.9975781,0.00004821014,0.0004000551,0.0009710756,0.000494842,0.0005077281],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005393442,0.001153441,0.0007154649,0.0003532237,0.0003184509,0.005146083,0.01089812,0.00009668324,0.8102648,0.00007740854,0.1558545,0.01458246],"study_design_scores_gemma":[0.001127585,0.0002728584,0.0001006842,0.00006439645,0.0004333286,0.0007528794,0.001120199,0.00004984111,0.6300536,0.001791108,0.3639264,0.0003071362],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9473552,0.002870927,0.001940418,0.001690865,0.01405844,0.0008849038,0.00007562752,0.0002100648,0.03091358],"genre_scores_gemma":[0.9875087,0.00008549172,0.004339586,0.0002539072,0.0004472812,0.00005078582,0.0004367784,0.00004080212,0.006836641],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2080719,"threshold_uncertainty_score":0.9999936,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03331286894283186,"score_gpt":0.2811114191246911,"score_spread":0.2477985501818592,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}