{"id":"W937474088","doi":"10.1016/j.imbio.2015.07.019","title":"Anti-citrullinated protein antibodies promote apoptosis of mature human Saos-2 osteoblasts via cell-surface binding to citrullinated heat shock protein 60","year":2015,"lang":"en","type":"article","venue":"Immunobiology","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Public Health Ontario","funders":"National Science Council","keywords":"Antibody; Heat shock protein; Molecular biology; Cell biology; Immunology; Chemistry; Medicine; Biology; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002504665,0.0003420088,0.0003204889,0.000242531,0.0001810471,0.0002983476,0.0001733075,0.0002715914,0.001933387],"category_scores_gemma":[0.0001589084,0.0002315009,0.0004087727,0.0001657866,0.0002529224,0.0001839616,0.0002198947,0.0007852715,0.000385721],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001889749,"about_ca_system_score_gemma":0.0002408768,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008378983,"about_ca_topic_score_gemma":0.001477177,"domain_scores_codex":[0.9997688,0.00004055476,0.00002023562,0.00002545368,0.00006449902,0.00008045811],"domain_scores_gemma":[0.9998685,0.00003716947,0.00002405825,0.00001840782,0.00002630297,0.00002546499],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000535975,0.0001050054,0.0003482072,0.00003912968,0.000008226853,0.00008790898,0.00003895795,0.00003054409,0.9975236,0.00006638889,0.00004953589,0.001166651],"study_design_scores_gemma":[0.0002114588,0.002001202,0.02755233,0.00001256455,0.00004737365,0.0004639642,0.0002418785,0.0009958842,0.9655493,0.0001508264,0.002764736,0.00000837553],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950545,0.00242758,0.00102196,0.0001179824,0.00007663437,0.00002213315,0.00008255168,0.00001847133,0.001178295],"genre_scores_gemma":[0.9957867,0.001102933,0.000561206,0.00009228378,0.00002718004,0.00002839488,0.0002060661,0.000006872906,0.00218819],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001933387,"threshold_uncertainty_score":0.006467879,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01723017710968261,"score_gpt":0.2809443205769949,"score_spread":0.2637141434673123,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}