{"id":"W939371937","doi":"","title":"RD3 As A New Modulator Of Retinal Photoreceptor Guanylyl Cyclase (RetGC): A Strong Inhibition Of RetGC Activity And The Effects Of Retinal Disease-linked Mutations","year":2011,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Retinal; Guanylate cyclase; Biology; Cell biology; Receptor; Genetics; Botany","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002903629,0.0004629722,0.0003987379,0.0001948533,0.000326527,0.0003729568,0.0004530464,0.0005001177,0.001387369],"category_scores_gemma":[0.0001900674,0.0001638558,0.0003052246,0.0001775307,0.0004920221,0.0002669648,0.0002317092,0.0009575462,0.0002844529],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000619636,"about_ca_system_score_gemma":0.0003424193,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001378183,"about_ca_topic_score_gemma":0.001695038,"domain_scores_codex":[0.9998797,0.00002663919,0.00001336838,0.00002384972,0.00003366931,0.00002279577],"domain_scores_gemma":[0.9999174,0.0000176514,0.0000126747,0.00001429921,0.000008828308,0.00002924073],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003052994,0.00001758557,0.0001034655,0.00002527925,0.000007838215,0.0001389306,0.00001122808,0.00007194922,0.9978022,0.00030584,0.000085306,0.001125099],"study_design_scores_gemma":[0.00005646176,0.0001892238,0.001168074,0.00000313685,0.00002646158,0.0005011592,0.00000963619,0.000476567,0.9945896,0.0001117366,0.002861738,0.000006226715],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.975616,0.01110567,0.006875522,0.0009980031,0.0002310592,0.00006149108,0.0006111473,0.0003378715,0.004163267],"genre_scores_gemma":[0.9933479,0.001464078,0.002867933,0.0001586546,0.00003550186,0.00002955186,0.0003189222,0.00004609031,0.001731316],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001387369,"threshold_uncertainty_score":0.004641175,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01968581938888941,"score_gpt":0.289637386208504,"score_spread":0.2699515668196146,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}