{"id":"W976018201","doi":"","title":"Abstract 13988: Class II Major Histocompatibility Complex Transactivator (CIITA) Knockdown Prevents Immune Rejection of Allogeneic Bone Marrow Stem Cells in Cardiac Regeneration","year":2014,"lang":"en","type":"article","venue":"Circulation","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"","keywords":"CIITA; Mesenchymal stem cell; Gene knockdown; Immunology; Cancer research; Immune system; Major histocompatibility complex; Stem cell; MHC class II; Bone marrow; Medicine; Biology; Cell biology; Cell culture","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001605784,0.0005829656,0.0004631242,0.000349608,0.0001827999,0.0003346782,0.0004144736,0.0004531155,0.006910475],"category_scores_gemma":[0.00007842383,0.0002031463,0.0003354638,0.0002152667,0.0003733029,0.0001939999,0.0002407553,0.001116227,0.001662081],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002123127,"about_ca_system_score_gemma":0.0003908434,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004048217,"about_ca_topic_score_gemma":0.000431532,"domain_scores_codex":[0.9997209,0.00002863461,0.0000355218,0.00006144879,0.00008601823,0.00006744814],"domain_scores_gemma":[0.9998659,0.00001082513,0.00004476621,0.00001185788,0.00001085805,0.00005570081],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000178794,0.00006194704,0.00005906959,0.0000733197,0.000005422115,0.00002900125,0.000009996649,0.00002440032,0.9983546,0.00006932779,0.000159763,0.0009742324],"study_design_scores_gemma":[0.00009398434,0.000514963,0.002489896,0.00001785936,0.00003072084,0.0002082741,0.00002880566,0.0004118356,0.9915468,0.00003351191,0.004619051,0.000004362497],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9846815,0.003451764,0.004320931,0.00034931,0.0002668615,0.0001127995,0.001737053,0.0005183927,0.004561371],"genre_scores_gemma":[0.9790507,0.001807226,0.00248633,0.0001917233,0.00005225563,0.0003053751,0.002379883,0.0001037667,0.01362279],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006910475,"threshold_uncertainty_score":0.02311784,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03832809277051274,"score_gpt":0.2832398086617588,"score_spread":0.2449117158912461,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}