{"id":"W978290998","doi":"10.1021/acs.biochem.5b00644","title":"Asparagine Repeat Peptides: Aggregation Kinetics and Comparison with Glutamine Repeats","year":2015,"lang":"en","type":"article","venue":"Biochemistry","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Air Force Office of Scientific Research; Instituto de Salud Carlos III; National Cancer Institute; Seventh Framework Programme; Water Resources Research Institute, North Carolina State University; Basic Energy Sciences; National Chung-Hsing University; Ministry of Science and Technology, Taiwan; Korea Institute of Science and Technology Information; University of Alberta; Ministerio de Educación, Cultura y Deporte; Canada Research Chairs; National Natural Science Foundation of China; National Research Foundation of Korea; National Research Foundation Singapore; National Center for Research Resources; Canada Foundation for Innovation; Dow Chemical Company; Canadian Institutes of Health Research; Central Taiwan University of Science and Technology; Government of Canada; Directorate for Engineering; University of Connecticut","keywords":"Asparagine; Glutamine; Biochemistry; Direct repeat; Tandem repeat; Biology; Amino acid; Genetics; Chemistry; Biophysics; Genome; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001474908,0.0001584317,0.000143555,0.00002215889,0.00004323464,0.00004265876,0.0001225979,0.0001249204,0.000003754692],"category_scores_gemma":[0.0001811761,0.0001355485,0.00002553387,0.00008152972,0.000122912,0.000004055092,0.00009789015,0.00009803203,0.000004205567],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002582801,"about_ca_system_score_gemma":0.00007737587,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002500871,"about_ca_topic_score_gemma":0.00001433803,"domain_scores_codex":[0.9989694,0.00002103345,0.0001704704,0.0003752848,0.0002194909,0.0002442963],"domain_scores_gemma":[0.9991143,0.000008000368,0.00007455276,0.0003936732,0.0001532289,0.0002562755],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000199647,0.00005572438,0.01309425,0.00003789762,0.00002903147,0.00001242166,0.00002567073,0.00003235577,0.9794917,0.00000318958,0.004499766,0.002518408],"study_design_scores_gemma":[0.0009606497,0.0005286328,0.001140678,0.00004426283,0.00001432423,0.000110325,0.0002090355,0.000479451,0.9919187,0.000008586706,0.004377009,0.0002083495],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953027,0.001800778,0.0006814782,0.0001907106,0.00002376397,0.0001020361,0.000007532857,0.00002073279,0.001870274],"genre_scores_gemma":[0.9921494,0.00007445862,0.001914487,0.00006298206,0.000216783,0.00001259454,0.0002062921,0.00002103538,0.005341997],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01242706,"threshold_uncertainty_score":0.5527508,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0210971020995624,"score_gpt":0.2805195126186786,"score_spread":0.2594224105191162,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}