{"id":"W97968797","doi":"10.1023/a:1015249530156","title":"Ferric hydroxamate binding protein FhuD from Escherichia coli: mutants in conserved and non-conserved regions","year":2002,"lang":"en","type":"article","venue":"BioMetals","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Periplasmic space; Biochemistry; Bacterial outer membrane; ATP-binding cassette transporter; Siderophore; Membrane transport protein; Integral membrane protein; Biology; Transport protein; Membrane protein; Binding protein; Escherichia coli; Inner membrane; Protein structure; Ferrichrome; Chemistry; Membrane; Transporter; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003168076,0.00100648,0.0007550706,0.0006301425,0.0004548112,0.0006388948,0.001085154,0.0008723684,0.001478257],"category_scores_gemma":[0.0004394276,0.0003995704,0.0004687653,0.0006378569,0.0008852324,0.000351635,0.0006662174,0.001149676,0.0006460373],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000746248,"about_ca_system_score_gemma":0.0006661882,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004778784,"about_ca_topic_score_gemma":0.002738341,"domain_scores_codex":[0.9996638,0.00006038937,0.00004563222,0.00003485735,0.0001237011,0.00007163096],"domain_scores_gemma":[0.9995633,0.0001272097,0.0000892884,0.00004673773,0.00004651433,0.0001270618],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005984791,0.0001364894,0.0004930627,0.00007333827,0.00002586923,0.0003131026,0.00004052118,0.0001919092,0.9958182,0.0003007787,0.00006621998,0.001942091],"study_design_scores_gemma":[0.00006306912,0.0001673043,0.003805378,0.00001429373,0.00004791233,0.0008546581,0.00011308,0.001237814,0.992319,0.0001092991,0.001245862,0.00002226406],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931537,0.0005786495,0.004311878,0.000251643,0.00007680221,0.00005703636,0.0005287585,0.0001512275,0.0008903564],"genre_scores_gemma":[0.9947358,0.0002203286,0.002351173,0.00007494493,0.00001923248,0.00003150764,0.0007669806,0.00008347836,0.001716648],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004778784,"threshold_uncertainty_score":0.009501934,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02204779961144239,"score_gpt":0.2259761620165683,"score_spread":0.2039283624051259,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}