Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019
Pourquoi ce travail est-il dans la base ?
Une base qui oublie comment elle a trouvé un travail ne peut pas être vérifiée. Voici les voies qui ont admis celui-ci.
Aucune affiliation canadienne. Une base fondée sur la seule affiliation (le devis habituel) n'aurait jamais vu ce travail. C'est l'un des travaux qui justifient l'inversion de la base.
Résumé
BACKGROUND: In an era of shifting global agendas and expanded emphasis on non-communicable diseases and injuries along with communicable diseases, sound evidence on trends by cause at the national level is essential. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) provides a systematic scientific assessment of published, publicly available, and contributed data on incidence, prevalence, and mortality for a mutually exclusive and collectively exhaustive list of diseases and injuries. METHODS: GBD estimates incidence, prevalence, mortality, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life-years (DALYs) due to 369 diseases and injuries, for two sexes, and for 204 countries and territories. Input data were extracted from censuses, household surveys, civil registration and vital statistics, disease registries, health service use, air pollution monitors, satellite imaging, disease notifications, and other sources. Cause-specific death rates and cause fractions were calculated using the Cause of Death Ensemble model and spatiotemporal Gaussian process regression. Cause-specific deaths were adjusted to match the total all-cause deaths calculated as part of the GBD population, fertility, and mortality estimates. Deaths were multiplied by standard life expectancy at each age to calculate YLLs. A Bayesian meta-regression modelling tool, DisMod-MR 2.1, was used to ensure consistency between incidence, prevalence, remission, excess mortality, and cause-specific mortality for most causes. Prevalence estimates were multiplied by disability weights for mutually exclusive sequelae of diseases and injuries to calculate YLDs. We considered results in the context of the Socio-demographic Index (SDI), a composite indicator of income per capita, years of schooling, and fertility rate in females younger than 25 years. Uncertainty intervals (UIs) were generated for every metric using the 25th and 975th ordered 1000 draw values of the posterior distribution. FINDINGS: Global health has steadily improved over the past 30 years as measured by age-standardised DALY rates. After taking into account population growth and ageing, the absolute number of DALYs has remained stable. Since 2010, the pace of decline in global age-standardised DALY rates has accelerated in age groups younger than 50 years compared with the 1990-2010 time period, with the greatest annualised rate of decline occurring in the 0-9-year age group. Six infectious diseases were among the top ten causes of DALYs in children younger than 10 years in 2019: lower respiratory infections (ranked second), diarrhoeal diseases (third), malaria (fifth), meningitis (sixth), whooping cough (ninth), and sexually transmitted infections (which, in this age group, is fully accounted for by congenital syphilis; ranked tenth). In adolescents aged 10-24 years, three injury causes were among the top causes of DALYs: road injuries (ranked first), self-harm (third), and interpersonal violence (fifth). Five of the causes that were in the top ten for ages 10-24 years were also in the top ten in the 25-49-year age group: road injuries (ranked first), HIV/AIDS (second), low back pain (fourth), headache disorders (fifth), and depressive disorders (sixth). In 2019, ischaemic heart disease and stroke were the top-ranked causes of DALYs in both the 50-74-year and 75-years-and-older age groups. Since 1990, there has been a marked shift towards a greater proportion of burden due to YLDs from non-communicable diseases and injuries. In 2019, there were 11 countries where non-communicable disease and injury YLDs constituted more than half of all disease burden. Decreases in age-standardised DALY rates have accelerated over the past decade in countries at the lower end of the SDI range, while improvements have started to stagnate or even reverse in countries with higher SDI. INTERPRETATION: As disability becomes an increasingly large component of disease burden and a larger component of health expenditure, greater research and development investment is needed to identify new, more effective intervention strategies. With a rapidly ageing global population, the demands on health services to deal with disabling outcomes, which increase with age, will require policy makers to anticipate these changes. The mix of universal and more geographically specific influences on health reinforces the need for regular reporting on population health in detail and by underlying cause to help decision makers to identify success stories of disease control to emulate, as well as opportunities to improve. FUNDING: Bill & Melinda Gates Foundation.
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
La notice
- Revue
- The Lancet
- Thématique
- Global Maternal and Child Health
- Domaine
- Medicine
- Établissements canadiens
- —
- Organismes subventionnaires
- European and Developing Countries Clinical Trials PartnershipEunice Kennedy Shriver National Institute of Child Health and Human DevelopmentNational Institute of Child Health and Human DevelopmentNational Institute of Diabetes and Digestive and Kidney DiseasesFogarty International CenterNational Institute of Mental HealthNational Institute on AgingNorwegian Institute of Public HealthNIHR Oxford Biomedical Research CentreHealth and Social Care Research and Development DivisionRussian Academy of SciencesDepartment of Science and Innovation, South AfricaNational Health and Medical Research CouncilEuropean Social FundMedical Research CouncilSeventh Framework ProgrammeRegion SjællandManchester Biomedical Research CentreHorizon 2020University of California BerkeleySixth Framework ProgrammeGillings School of Public HealthNational Institutes of HealthPrograma Operacional Temático Factores de CompetitividadeMinistério da SaúdeUniversity of MichiganBHF Centre of Research Excellence, OxfordUniversidad de Costa RicaCoordenação de Aperfeiçoamento de Pessoal de Nível SuperiorUniversity of GhanaFoundation for Education and European CultureWorld Health OrganizationFundação de Amparo à Pesquisa do Estado de Minas GeraisUniversiti Kebangsaan MalaysiaChandigarh UniversityUnitatea Executiva pentru Finantarea Invatamantului Superior, a Cercetarii, Dezvoltarii si InovariiKuwait UniversityDanmarks GrundforskningsfondNational Institute for Health Research Health Protection Research UnitVetenskapsrådetState Government of VictoriaMinistrstvo za zdravjeFundação de Amparo à Pesquisa do Estado do Rio Grande do SulChief Scientist Office, Scottish Government Health and Social Care DirectorateMinistero della SaluteCouncil for the Development of Social Science Research in AfricaInstituto de Salud Carlos IIINational Natural Science Foundation of ChinaBundesministerium für Bildung und ForschungBritish Heart FoundationMinistry of Education, Culture, Sports, Science and TechnologyConselho Nacional de Desenvolvimento Científico e TecnológicoPublic Health AgencyMinistério da Ciência, Tecnologia e Ensino SuperiorDepartment of Biotechnology, Ministry of Science and Technology, IndiaThe Wellcome Trust DBT India AllianceNational Institute for Health and Care ResearchRoyal College of PhysiciansNational Research FoundationComunidad de MadridNational Heart Foundation of AustraliaDeakin UniversityUniversität HeidelbergAutoritatea Natională pentru Cercetare StiintificăUniversity of BristolXiamen UniversityEngineering and Physical Sciences Research CouncilEuropean CommissionFred Hollows FoundationEuropean Regional Development FundUnited States Agency for International DevelopmentDepartment of Health and Social CareEuropean Research CouncilSistema Nacional de InvestigadoresMax-Planck-GesellschaftBrien Holden Vision InstituteKing's College LondonFundação para a Ciência e a TecnologiaAcademy of Medical SciencesSchweizerischer Nationalfonds zur Förderung der Wissenschaftlichen ForschungKasturba Medical College, ManipalCardiovascular Medical Research and Education FundEuropean Centre for Disease Prevention and ControlManipal Academy of Higher EducationMinistarstvo Prosvete, Nauke i Tehnološkog RazvojaNational Rosacea SocietyPublic Health EnglandNational Authority for Scientific Research and InnovationDuke UniversityMinisterio de Ciencia, Innovación y UniversidadesScottish GovernmentGovernment of South AustraliaUniversity Grants CommissionFifth Framework ProgrammeKing's College Hospital NHS Foundation TrustEconomic Growth Center, Yale UniversityPublic Health Agency of CanadaQueensland HealthWellcome TrustGuy's and St Thomas' NHS Foundation TrustChina Medical UniversitySt. Jude Children's Research HospitalHealth Research Council of New ZealandUniversity of New South WalesYale UniversityEconomic and Social Research CouncilBill and Melinda Gates FoundationUniversity of MelbourneUniversity of Calgary
- Mots-clés
- Burden of diseaseMedicineDiseaseDisease burdenEnvironmental healthPathology
- Résumé présent dans OpenAlex
- oui