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Record W1421559795

Restless legs syndrome in children.

2006· article· en· W1421559795 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

aboutThe title or abstract carries a Canadian signal from the geographic lexicon.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenuePubMed · 2006
Typearticle
Languageen
FieldMedicine
TopicRestless Legs Syndrome Research
Canadian institutionsnot available
Fundersnot available
KeywordsRestless legs syndromeGrowing painsPopulationPediatricsPsychologyPsychiatryMedicineNeurology
DOInot available

Abstract

fetched live from OpenAlex

Restless legs syndrome (RLS) is a neurologic disorder that was first described in the medical literature by T. Willis in 1672.[1,2] More than 250 years later, in 1945, Karl Ekbom applied the phrase “restless legs” to the syndrome.[3,4] Ekbom later wrote a paper on “growing pains” and “restless legs” and differentiated between them because growing pains were generally presumed to last only through childhood, whereas RLS had an early onset but was believed to persist into adulthood.[3–5] In 1960, Brenning noted that complaints of growing pains in children correlated with a higher risk of developing RLS-like symptoms as adults.[3,4] Primary RLS is believed to be an autosomal dominant disorder and, recently, scientists located a gene associated with RLS susceptibility on chromosome 12q for French-Canadian families, 14q for an Italian family, and 9p for 2 American families.[6,7] RLS is a sensory and motor disorder characterized by an uncontrollable sensation in the legs accompanied by an irresistible urge to move the legs, which usually results in partial or complete resolution immediately, albeit transiently.[7] There are many subtle variations of this disorder. To complicate matters, the diagnosis is purely clinical and thus depends on accurate historians to convey their subjective complaints. This poses a problem, especially in children. Consequently, RLS in children is believed to be underdiagnosed. Because primary care physicians typically comprise the frontline for the diagnosis and treatment of this disorder, accurate assessment by this physician population is critical. Children with RLS can present with conduct problems including aggression, inattention, hyperactivity, and daytime somnolence because of an inability to sleep or difficulty maintaining sleep. These symptoms may result from an associated periodic limb movement disorder (PLMD) or other problems such as aches and pains.[8] The consequences of RLS can be serious and include unsatisfactory performance in school, poor social development, and abnormal social interactions resulting in incorrect diagnoses of various psychiatric illnesses, including attention deficit hyperactivity disorder (ADHD), among others. Readers are encouraged to respond to George Lundberg, MD, Editor of MedGenMed, for the editor's eyes only or for possible publication via email: ten.epacsdem@grebdnulg

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.021
Threshold uncertainty score0.534

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.022
GPT teacher head0.261
Teacher spread0.238 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it