Effects of cold shock and cortisol on heat shock protein levels in rainbow trout
Bibliographic record
Abstract
The effect of cold shock and increased levels of circulating cortisol on heat shock proteins (Hsp) levels in rainbow trout (Oncorhynchus mykiss) were examined. Cold shock: When the cultured hepatocytes were exposed to cold (at 4°C for 2h), Hsp 70 level in hepatocytes were similar to that in control. However, Hsp 30 was markedly induced by cold shock. Cortisol: The high concentration of circulating cortisol (pharmacological levels) was found to reduce the Hsp 70 levels in liver and gill of cortisol implanted fish (50 μg cortisol/g body weight) exposed to heat shock (at 22°C for 2h) compared to the sham. These results suggest that the expressions of Hsp 30 and 70 in cell may be affected by cold stress response and circulating cortisol levels in fish, respectively. Furthermore, cellular stress response, such as Hsp expression, might be related with neuroendocrine/endocrine system in fish.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".