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Record W1573898492

Hybridization Number on Three Trees

2014· preprint· en· W1573898492 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenuearXiv (Cornell University) · 2014
Typepreprint
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenome Rearrangement Algorithms
Canadian institutionsDalhousie University
Fundersnot available
KeywordsPhylogenetic treePhylogenetic networkCombinatoricsConnection (principal bundle)MathematicsBinary logarithmGeneralizationBinary treeTree (set theory)Time complexityComputer scienceAlgorithmBiologyGenetics
DOInot available

Abstract

fetched live from OpenAlex

Phylogenetic networks are leaf-labelled directed acyclic graphs that are used to describe nontreelike evolutionary histories and are thus a generalization of phylogenetic trees. The hybridization number of a phylogenetic network is the sum of all indegrees minus the number of nodes plus one. The Hybridization Number problem takes as input a collection of phylogenetic trees and asks to construct a phylogenetic network that contains an embedding of each of the input trees and has a smallest possible hybridization number. We present an algorithm for the Hybridization Number problem on three binary phylogenetic trees on n leaves, which runs in time O(c k poly(n)), with k the hybridization number of an optimal network and c some positive constant. For the case of two trees, an algorithm with running time O(3.18 k n) was proposed before whereas an algorithm with running time O(c k poly(n)) for more than two trees had prior to this article remained elusive. The algorithm for two trees uses the close connection to acyclic agreement forests to achieve a linear exponent in the running time, while previous algorithms for more than two trees (explicitly or implicitly) relied on a brute force search through all possible underlying network topologies, leading to running times that are not O(c k poly(n)), for any c. The connection to acyclic agreement forests is much weaker for more than two trees, so even given the right agreement forest, the reconstruction of the network poses major challenges. We prove novel structural results that allow us to reconstruct a network without having to guess the underlying topology. Our techniques generalize to more than three input trees with the exception of one key lemma that maps nodes in the network to tree nodes and, thus,

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.484
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.039
GPT teacher head0.184
Teacher spread0.145 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it