Magnetic resonance imaging and prediction of outcome in patients with major depressive disorder
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Review of MRI findings predicting treatment outcome in depression; clinical neuroscience.
It reviews clinical applications of neuroimaging for depression rather than studying evidence synthesis or research practice.
Clinical review of MRI predictors of treatment outcome in major depression; medical imaging, not metaresearch.
Abstract
Whether magnetic resonance imaging studies can provide useful information to clinicians who treat people with major depressive disorder remains to be established. There are, however, several recent findings that suggest that likelihood of response may be predicted by imaging findings. For example, morphometric studies have examined whether hippocampus volume is associated with clinically meaningful outcomes such as response to treatment. In general, patients who remit have larger pretreatment hippocampus volumes bilaterally compared with those who do not remit. There are similar preliminary findings for the anterior cingulate cortex. There are also a number of functional imaging studies that have identified different activity patterns in those who are likely to respond to treatment compared with those who are not. Using positron emission tomography, investigators have reported different patterns of response to treatment in those treated with medication compared with those treated with psychotherapy. Some of the potential barriers to the routine use of imaging in psychiatric practice are reviewed briefly.
Stored with the screening record, where it is evidence for the labels above.
The record
- Venue
- Journal of Psychiatry and Neuroscience
- Topic
- Functional Brain Connectivity Studies
- Field
- Neuroscience
- Canadian institutions
- University of Calgary
- Funders
- —
- Keywords
- Magnetic resonance imagingAnterior cingulate cortexFunctional magnetic resonance imagingNeuroimagingMajor depressive disorderHippocampusPositron emission tomographyMedicinePsychologyPsychiatryNeuroscienceClinical psychologyRadiologyCognition
- Has abstract in OpenAlex
- yes